ABRA

Description		actin binding Rho activating protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Actin Cytoskeleton Myofibril Sarcomere
	Molecular Function	Actin Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase II Protein Import Into Nucleus Protein Transport Actin Cytoskeleton Organization Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Intraocular pressure ( 30054594 31959993) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: ABLIM2 ACTA1 ACTB ACTC1 PPP1R18 TRAPPC2
Entrez ID		137735
HPRD ID		11608
Ensembl ID		ENSG00000174429
Uniprot IDs		Q8N0Z2
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Actin Cytoskeleton Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Blood Microparticle Lamellipodium Myosin Binding Sarcomere Filopodium Cell Body Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Structural Constituent Of Cytoskeleton Cytoskeleton Regulation Of Norepinephrine Uptake Transporter Regulator Activity Regulation Of Transepithelial Transport Protein Localization To Adherens Junction Dense Body Cytoplasmic Actin-based Contraction Involved In Cell Motility Muscle Contraction Morphogenesis Of A Polarized Epithelium Structural Constituent Of Postsynaptic Actin Cytoskeleton Striated Muscle Thin Filament Muscle System Process Actin Filament Organization BBAF Complex Tat Protein Binding Nitric-oxide Synthase Regulator Activity Postsynaptic Actin Cytoskeleton Cytoskeleton Organization Cytoplasm Brahma Complex Nitric-oxide Synthase Binding Apical Protein Localization RSC-type Complex Adherens Junction Assembly NpBAF Complex GBAF Complex Cellular Component Assembly Cardiac Myofibril Assembly TRAPPII Protein Complex TRAPP Complex TRAPPIII Protein Complex Organelle Organization NBAF Complex Postsynaptic Actin Cytoskeleton Organization Actin-myosin Filament Sliding Actin Cytoskeleton Organization Protein Localization To Cell-cell Junction
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