ABLIM2

Description		actin binding LIM protein family member 2
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GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Cytoskeleton Organization Lamellipodium Assembly
Pathways		DCC mediated attractive signaling
Drugs
Diseases
GWAS		Cognitive function ( 28808816) Diffusing capacity of carbon monoxide ( 30694715) Early onset periodontitis x smoking status interaction ( 31537151) Irritable bowel syndrome ( 29626450) Post bronchodilator FEV1 in COPD ( 26634245) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Triacylglyceride levels ( 31551469)
Interacting Genes		6 interacting genes: ABRA AHNAK2 ATP6V0A1 MLIP SREBF2 TTN
Entrez ID		84448
HPRD ID		10623
Ensembl ID		ENSG00000163995
Uniprot IDs		A0A140VK02 F5GYR0 Q6H8Q1
PDB IDs		1V6G 1WIG 2L3X
Enriched GO Terms of Interacting Partners?		Endosomal Lumen Acidification Proton-transporting V-type ATPase, V0 Domain Cytoplasm Regulation Of Macroautophagy Regulation Of Metabolic Process Regulation Of Autophagy Synaptic Vesicle Lumen Acidification Proton-transporting V-type ATPase Complex Vacuolar Proton-transporting V-type ATPase, V0 Domain Vacuolar Proton-transporting V-type ATPase Complex Positive Regulation Of Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process Response To Sterol Depletion Regulation Of Amyloid-beta Clearance Negative Regulation Of Amyloid-beta Clearance Positive Regulation Of Cholesterol Storage SREBP Signaling Pathway Negative Regulation Of Cholesterol Efflux Regulation Of Gene Expression Positive Regulation Of Lipid Storage Cellular Response To Laminar Fluid Shear Stress Cellular Response To Sterol Depletion SREBP-SCAP-Insig Complex C-8 Sterol Isomerase Activity Negative Regulation Of Cholesterol Transport Positive Regulation Of Macromolecule Biosynthetic Process Response To Laminar Fluid Shear Stress Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Establishment Of Protein Localization Titin-telethonin Complex Protein Kinase A Signaling Muscle Alpha-actinin Binding Mitotic Chromosome Condensation Detection Of Muscle Stretch Protein Kinase Regulator Activity Structural Molecule Activity Conferring Elasticity Actin-myosin Filament Sliding Striated Muscle Thin Filament Myosin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Actin Cytoskeleton Organization Actin Cytoskeleton Cardiac Myofibril Assembly Sarcomerogenesis Muscle Filament Sliding Actinin Binding Telethonin Binding Skeletal Muscle Thin Filament Assembly Sarcolemma Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
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