RAD54L and RAD51

Number of citations of the paper that reports this interaction (PMID 12205100)
41

Data Source:
HPRD (in vitro, in vivo)

		RAD54L	RAD51
Gene Name		RAD54-like (S. cerevisiae)	RAD51 recombinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nuclear Chromosome Condensed Chromosome Condensed Nuclear Chromosome Lateral Element Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Microtubule Organizing Center PML Body Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding Annealing Helicase Activity	Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding Protein C-terminus Binding Identical Protein Binding Single-stranded DNA-dependent ATPase Activity DNA Polymerase Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Strand Renaturation DNA Repair DNA Recombination Meiotic Nuclear Division Response To Ionizing Radiation Response To Drug Chromosome Organization	Double-strand Break Repair Via Homologous Recombination DNA Recombinase Assembly DNA Unwinding Involved In DNA Replication DNA Repair Double-strand Break Repair DNA Recombination Mitotic Recombination Cellular Response To DNA Damage Stimulus Meiotic Nuclear Division Reciprocal Meiotic Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA Ligation Protein Homooligomerization Cellular Response To Ionizing Radiation Cellular Response To Camptothecin
Pathways			Assembly of the RAD51-ssDNA nucleoprotein complex Homologous DNA pairing and strand exchange Meiotic recombination Homologous Recombination Repair Homologous recombination repair of replication-independent double-strand breaks Double-Strand Break Repair Presynaptic phase of homologous DNA pairing and strand exchange
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: RAD51 WDYHV1	42 interactors: ABL1 ATM ATRX BCCIP BLM BRCA1 BRCA2 CASP3 CASP7 CHD3 CHEK1 DMC1 DNAJA3 ERCC2 FANCD2 FBXO18 HID1 HNRNPC IRS1 MDC1 NXF1 PFN1 RAD18 RAD51AP1 RAD51AP2 RAD51C RAD52 RAD54B RAD54L RPA1 RPA3 SFR1 SUMO1 SWI5 SWSAP1 TP53 UBE2I UGDH UHRF2 VIM WRN ZDHHC17
Entrez ID		8438	5888
HPRD ID		04683	01557
Ensembl ID		ENSG00000085999	ENSG00000051180
Uniprot IDs		A8K996 Q92698	Q06609
PDB IDs			1B22 1N0W
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA Ligation Cellular Response To Camptothecin Response To Camptothecin DNA Recombinase Assembly Regulation Of Double-strand Break Repair Via Homologous Recombination DNA Unwinding Involved In DNA Replication Regulation Of Double-strand Break Repair Mitotic Recombination Cellular Response To Alkaloid Reciprocal Meiotic Recombination Cellular Response To Ionizing Radiation Regulation Of DNA Repair Regulation Of DNA Recombination DNA Duplex Unwinding DNA Geometric Change Double-strand Break Repair Via Homologous Recombination Recombinational Repair Meiosis I DNA-dependent DNA Replication Regulation Of Response To DNA Damage Stimulus Cellular Response To Radiation Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Response To Alkaloid Double-strand Break Repair Protein-DNA Complex Assembly Meiotic Nuclear Division	DNA Metabolic Process DNA Repair Cellular Response To DNA Damage Stimulus Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination Cellular Response To Stress Response To Stress Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Radiation Cellular Nitrogen Compound Metabolic Process Chromosome Organization Response To Ionizing Radiation Organelle Organization Cell Cycle Nitrogen Compound Metabolic Process Cellular Response To Stimulus DNA Duplex Unwinding DNA Geometric Change Response To Abiotic Stimulus Regulation Of Cell Cycle Response To Stimulus Cell Cycle Process DNA-dependent DNA Replication DNA Replication Signal Transduction In Response To DNA Damage Meiotic Nuclear Division Cellular Response To Ionizing Radiation DNA Conformation Change Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Cell Aging Response To UV Meiotic Cell Cycle Cellular Response To Radiation DNA Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Process Cellular Metabolic Process Replication Fork Processing Cellular Response To Hydroxyurea Intrinsic Apoptotic Signaling Pathway Meiosis I Response To Gamma Radiation Signal Transduction By P53 Class Mediator DNA Recombinase Assembly Regulation Of Response To DNA Damage Stimulus
Tagcloud ?		atlas biologically cgi cpg e2f1 false fanca focussing gpx4 hdac11 hgsoc island loci methylation nkd1 ovarian permutation pfs platinum prdx2 recql4 represented serous sided tcga vegfa vegfb vegfc vegfs	boundary box cerevisiae consisting damaging declined delta dosage dsc1 elements enhances fluctuate fluctuation frequency mbf1 mbp1 mcb meiosis meiotic mitotic mlu rad54 recombination saccharomyces spore sporulation swi6 transcript viability
Tagcloud (Difference) ?		atlas biologically cgi cpg e2f1 false fanca focussing gpx4 hdac11 hgsoc island loci methylation nkd1 ovarian permutation pfs platinum prdx2 recql4 represented serous sided tcga vegfa vegfb vegfc vegfs	boundary box cerevisiae consisting damaging declined delta dosage dsc1 elements enhances fluctuate fluctuation frequency mbf1 mbp1 mcb meiosis meiotic mitotic mlu rad54 recombination saccharomyces spore sporulation swi6 transcript viability
Tagcloud (Intersection) ?