GFM2 and VPS52

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GFM2	VPS52
Gene Name		G elongation factor, mitochondrial 2	vacuolar protein sorting 52 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix	Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Translation Elongation Factor Activity GTPase Activity GTP Binding	Protein Binding Syntaxin Binding
	Biological Process	Organelle Organization Mitochondrial Translation Ribosome Disassembly Mitochondrial Translational Elongation Mitochondrial Translational Termination	Ectodermal Cell Differentiation Protein Transport Embryonic Ectodermal Digestive Tract Development
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: BANP TRIM27 TRIM9 VPS52	49 interactors: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 KANK2 KIAA1217 KIF5B KLC3 LMO4 MAPK3 METTL13 MFAP1 MRPL11 NFKBIB NOP2 PPP1R18 PRKAA1 PRKAA2 RAB4A RNF41 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS51 VPS53 VPS54 WTAP ZMAT2
Entrez ID		84340	6293
HPRD ID		09413	09142
Ensembl ID		ENSG00000164347	ENSG00000223501
Uniprot IDs		Q969S9	B4DNI9 Q8N1B4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Secretion By Cell Embryonic Ectodermal Digestive Tract Development Negative Regulation Of SNARE Complex Assembly Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Secretion Negative Regulation Of Calcium Ion Import Ectodermal Cell Differentiation Regulation Of Protein Complex Assembly Regulation Of SNARE Complex Assembly Interferon-gamma Secretion Negative Regulation Of Vesicle Fusion Negative Regulation Of Transport Protein Localization Negative Regulation Of Viral Release From Host Cell Secretion By Cell Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcium Ion-dependent Exocytosis Protein Ubiquitination Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Protein Modification By Small Protein Conjugation Regulation Of Calcium Ion Import Cellular Localization Secretion Ectoderm Development Regulation Of Secretion Protein K63-linked Ubiquitination Cytokine Secretion Protein Trimerization Negative Regulation Of Cytokine Secretion Negative Regulation Of Adaptive Immune Response Negative Regulation Of Exocytosis Regulation Of Vesicle Fusion Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Negative Regulation Of Calcium Ion Transport Embryonic Digestive Tract Development Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Organelle Organization Negative Regulation Of Transmembrane Transport Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis	Anion Homeostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Establishment Of Localization In Cell Insulin Receptor Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Energy Homeostasis TRIF-dependent Toll-like Receptor Signaling Pathway Autophagy Cellular Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Glycolytic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Transport MyD88-dependent Toll-like Receptor Signaling Pathway Fatty Acid Homeostasis Regulation Of Generation Of Precursor Metabolites And Energy Toll-like Receptor 4 Signaling Pathway Interleukin-1-mediated Signaling Pathway Endosomal Transport Cellular Response To Insulin Stimulus Gene Expression Regulation Of Circadian Rhythm Histone-serine Phosphorylation Cellular Response To Glucose Starvation Toll-like Receptor Signaling Pathway RNA Metabolic Process Regulation Of Glycolytic Process Response To Peptide Hormone Response To Hormone Negative Regulation Of TOR Signaling Response To Peptide Cholesterol Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cerebellar Molecular Layer Development Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of Autophagy Activation Of MAPK Activity Activation Of Innate Immune Response Organelle Disassembly Cellular Response To Peptide Hormone Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?			biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Difference) ?			biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Intersection) ?