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USP48 and DRD3
Number of citations of the paper that reports this interaction (PMID
24308971
)
0
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
USP48
DRD3
Gene Name
ubiquitin specific peptidase 48
dopamine receptor D3
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Plasma Membrane
Integral Component Of Plasma Membrane
Endocytic Vesicle
Cell Projection
Apical Part Of Cell
Molecular Function
Cysteine-type Endopeptidase Activity
Ubiquitin-specific Protease Activity
Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go
Protein Binding
Drug Binding
Protein Domain Specific Binding
D1 Dopamine Receptor Binding
Dopamine Binding
Biological Process
Protein Deubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Synaptic Transmission, Dopaminergic
Response To Amphetamine
Regulation Of Blood Volume By Renin-angiotensin
G-protein Coupled Receptor Internalization
Cellular Calcium Ion Homeostasis
G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Learning Or Memory
Learning
Locomotory Behavior
Positive Regulation Of Cell Proliferation
Visual Learning
Regulation Of Dopamine Secretion
Regulation Of Lipid Metabolic Process
Regulation Of CAMP Metabolic Process
Negative Regulation Of Sodium:proton Antiporter Activity
Positive Regulation Of Cytokinesis
Circadian Regulation Of Gene Expression
Response To Histamine
Social Behavior
Gastric Emptying
Positive Regulation Of Renal Sodium Excretion
Regulation Of Multicellular Organism Growth
Response To Cocaine
Dopamine Metabolic Process
Response To Drug
Response To Morphine
Regulation Of Circadian Sleep/wake Cycle, Sleep
Response To Ethanol
Negative Regulation Of Blood Pressure
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Acid Secretion
Behavioral Response To Cocaine
Negative Regulation Of Oligodendrocyte Differentiation
Arachidonic Acid Secretion
Negative Regulation Of Protein Secretion
Musculoskeletal Movement, Spinal Reflex Action
Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Protein Kinase B Signaling
Prepulse Inhibition
Negative Regulation Of Dopamine Receptor Signaling Pathway
Positive Regulation Of Dopamine Receptor Signaling Pathway
Regulation Of Locomotion Involved In Locomotory Behavior
Pathways
Drugs
Ziprasidone
Cabergoline
Ropinirole
Olanzapine
Clozapine
Sulpiride
Remoxipride
Pramipexole
Haloperidol
Lisuride
Apomorphine
Risperidone
Dopamine
Pimozide
Domperidone
Pergolide
Bromocriptine
Quetiapine
Levodopa
Aripiprazole
Chlorprothixene
Paliperidone
Yohimbine
Methotrimeprazine
Iloperidone
Rotigotine
Asenapine
Amisulpride
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
APP
DRD3
UBC
15 interactors:
CLIC6
EEF1B2
EEF1G
EPB41
EPB41L1
EPB41L2
FLNA
GIPC1
GNAI1
GRB2
MPDZ
NCK1
NCS1
RDX
USP48
Entrez ID
84196
1814
HPRD ID
15637
00540
Ensembl ID
ENSG00000090686
ENSG00000151577
Uniprot IDs
B7ZKS7
Q86UV5
E9PCM4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cell Cycle Process
Positive Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Regulation Of Cell Cycle Process
Visual Learning
Visual Behavior
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Associative Learning
Negative Regulation Of Catalytic Activity
Regulation Of Multicellular Organism Growth
Regulation Of Cell Cycle
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Neuromuscular Process
Response To Abiotic Stimulus
Learning
Notch Signaling Pathway
Adult Behavior
Circadian Rhythm
Positive Regulation Of Transcription, DNA-templated
Intracellular Receptor Signaling Pathway
Negative Regulation Of Sodium:proton Antiporter Activity
Synaptic Growth At Neuromuscular Junction
Gastric Emptying
Regulation Of Phosphorus Metabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Gene Expression
Locomotory Behavior
Positive Regulation Of Cellular Biosynthetic Process
Musculoskeletal Movement, Spinal Reflex Action
Positive Regulation Of Dopamine Receptor Signaling Pathway
Collateral Sprouting In Absence Of Injury
Learning Or Memory
Negative Regulation Of Neurogenesis
Regulation Of Developmental Growth
Cognition
Cellular Calcium Ion Homeostasis
Regulation Of Locomotion Involved In Locomotory Behavior
Negative Regulation Of Dopamine Receptor Signaling Pathway
Positive Regulation Of Proteolysis
Regulation Of Transcription From RNA Polymerase II Promoter
Calcium Ion Homeostasis
Rhythmic Process
Collateral Sprouting
Axon Midline Choice Point Recognition
Negative Regulation Of Cell Development
Cortical Actin Cytoskeleton Organization
Cortical Cytoskeleton Organization
Actin Cytoskeleton Organization
Actin Filament-based Process
Regulation Of Actin Filament Polymerization
Platelet Activation
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Cytoskeleton Organization
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Cap-dependent Translational Initiation
Positive Regulation Of Cap-independent Translational Initiation
Cell Activation
Cell Projection Assembly
Regulation Of Cellular Component Size
Regulation Of Protein Complex Assembly
Positive Regulation Of Translation In Response To Stress
Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Cytoplasmic Translation
Regulation Of Actin Cytoskeleton Organization
Regulation Of Protein Catabolic Process
Regulation Of Actin Filament-based Process
Peptidyl-serine Dephosphorylation
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Actin Filament Polymerization
Cell-cell Signaling
Blood Coagulation
Hemostasis
Negative Regulation Of Protein Catabolic Process
Positive Regulation Of Protein Polymerization
Posttranscriptional Regulation Of Gene Expression
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Regulation Of Protein Stability
Phosphatidylinositol-mediated Signaling
Regulation Of Cytoskeleton Organization
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Cell Projection Organization
Positive Regulation Of Protein Complex Assembly
Regulation Of Body Fluid Levels
Translational Elongation
Synaptic Transmission
Wound Healing
Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Substrate-dependent Cell Migration, Cell Extension
Positive Regulation Of Signal Transduction
Branching Involved In Labyrinthine Layer Morphogenesis
Tagcloud
?
admissions
binary
binomial
biweekly
calls
catechol
computerized
comt
crisis
exploratory
genotyping
heterozygote
homozygote
mcgill
met
monoamine
pain
painreportit
record
rs4680
rs6280
scd
ser9gly
sickle
telephone
utilization
val
val158met
zero
Tagcloud (Difference)
?
admissions
binary
binomial
biweekly
calls
catechol
computerized
comt
crisis
exploratory
genotyping
heterozygote
homozygote
mcgill
met
monoamine
pain
painreportit
record
rs4680
rs6280
scd
ser9gly
sickle
telephone
utilization
val
val158met
zero
Tagcloud (Intersection)
?