EVA1A and POLE4

		EVA1A	POLE4
Description		eva-1 homolog A, regulator of programmed cell death	DNA polymerase epsilon 4, accessory subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Nucleus Nucleoplasm Epsilon DNA Polymerase Complex ATAC Complex
	Molecular Function	Protein Binding	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Cardiac Left Ventricle Morphogenesis Energy Reserve Metabolic Process Autophagy Apoptotic Process Heart Development Post-embryonic Development Lung Development TOR Signaling Connective Tissue Replacement	DNA-templated DNA Replication DNA Biosynthetic Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex
Drugs			Cladribine
Diseases
GWAS		Chronotype ( 30696823) Gout ( 32238385) Seborrheic dermatitis ( 29203360)	Venous thromboembolism ( 33592630)
Interacting Genes		8 interacting genes: GYPA MAP1LC3B MS4A13 MTNR1B PTN SAT1 SGTB TSPAN4	7 interacting genes: HSPA13 NFYB POLE POLE2 POLE3 PRKAR1B UBE3A
Entrez ID		84141	56655
HPRD ID		07827	16238
Ensembl ID		ENSG00000115363	ENSG00000115350
Uniprot IDs		Q9H8M9	Q9NR33
PDB IDs
Enriched GO Terms of Interacting Partners?			Epsilon DNA Polymerase Complex DNA-directed DNA Polymerase Activity Leading Strand Elongation DNA-templated DNA Replication DNA Biosynthetic Process DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation DNA Replication DNA Synthesis Involved In DNA Repair Sperm Entry Positive Regulation Of Golgi Lumen Acidification Lactosylceramide Biosynthetic Process
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