SLC41A2 and KIR3DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC41A2	KIR3DL3
Description		solute carrier family 41 member 2	killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Monoatomic Cation Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity	Protein Binding
	Biological Process	Monoatomic Ion Transport Monoatomic Cation Transport Cobalt Ion Transport Iron Ion Transport Manganese Ion Transport Nickel Cation Transport Magnesium Ion Transport Metal Ion Transport Magnesium Ion Transmembrane Transport	Immune Response-regulating Signaling Pathway Cell Communication
Pathways		Metal ion SLC transporters
Drugs
Diseases
GWAS		Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		31 interacting genes: AQP6 CD79A CLN5 CREB3 EBP ERGIC3 ERVFRD-1 FATE1 FNDC9 FUT3 GJA5 GJB5 GPR151 GPR42 GPX8 IGFBP5 IL27RA KASH5 KIR3DL3 LDLRAD1 LEUTX LIME1 LMNA LY6G6C LYVE1 MFF PDCD1LG2 PVR SHISAL1 SSMEM1 TMEM237	23 interacting genes: ADAM33 AGTRAP ASIC1 C5 CD53 CMTM5 CTXN3 EDDM3B EMP3 GIMAP5 JAGN1 LAPTM5 NINJ2 OLFM4 SERP1 SLC35A1 SLC41A2 SMIM3 SYS1 TAFA2 TNMD UPK2 VAMP5
Entrez ID		84102	115653
HPRD ID		15389	17236
Ensembl ID		ENSG00000136052	ENSG00000242019
Uniprot IDs		Q96JW4	A0A8I5QEB2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane B Cell Receptor Complex	Membrane Inorganic Cation Transmembrane Transporter Activity
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