SLC41A2 and FUT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC41A2	FUT3
Description		solute carrier family 41 member 2	fucosyltransferase 3 (Lewis blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane Extracellular Exosome
	Molecular Function	Protein Binding Monoatomic Cation Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity	Protein Binding Fucosyltransferase Activity Transferase Activity Glycosyltransferase Activity 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase Activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Activity Alpha-(1->3)-fucosyltransferase Activity
	Biological Process	Monoatomic Ion Transport Monoatomic Cation Transport Cobalt Ion Transport Iron Ion Transport Manganese Ion Transport Nickel Cation Transport Magnesium Ion Transport Metal Ion Transport Magnesium Ion Transmembrane Transport	Protein Glycosylation Protein N-linked Glycosylation Protein O-linked Glycosylation Lipid Metabolic Process Sphingolipid Metabolic Process Ceramide Metabolic Process Oligosaccharide Metabolic Process Oligosaccharide Biosynthetic Process Cell-cell Recognition Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Migration Fucosylation Regulation Of Cell Population Proliferation Macromolecule Glycosylation
Pathways		Metal ion SLC transporters	Lewis blood group biosynthesis Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases
GWAS		Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)	Blood protein levels ( 30072576) Elevated serum carcinoembryonic antigen levels ( 24941225) N-glycan levels ( 21203500 21908519) Serum alkaline phosphatase levels ( 33547301) Serum cancer antigen 19.9 levels ( 31666285) Vitamin B12 levels ( 28334792)
Interacting Genes		31 interacting genes: AQP6 CD79A CLN5 CREB3 EBP ERGIC3 ERVFRD-1 FATE1 FNDC9 FUT3 GJA5 GJB5 GPR151 GPR42 GPX8 IGFBP5 IL27RA KASH5 KIR3DL3 LDLRAD1 LEUTX LIME1 LMNA LY6G6C LYVE1 MFF PDCD1LG2 PVR SHISAL1 SSMEM1 TMEM237	5 interacting genes: C3orf52 SEC22A SLC41A2 TRARG1 WWP2
Entrez ID		84102	2525
HPRD ID		15389	00196
Ensembl ID		ENSG00000136052	ENSG00000171124
Uniprot IDs		Q96JW4	A8K737 P21217
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane B Cell Receptor Complex
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