TMEM222 and LRRC59

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM222	LRRC59
Description		transmembrane protein 222	leucine rich repeat containing 59
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Dendrite Cell Projection	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondrial Nucleoid
	Molecular Function	Protein Binding	RNA Binding Protein Binding Cadherin Binding
	Biological Process		Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 31219225)
Interacting Genes		40 interacting genes: ABHD16A AQP6 BIK BSCL2 CD79A CLDN5 CLRN1 COMT CRB3 CREB3 CREB3L1 EBP ELOVL4 ERG28 ERGIC3 EVI2B FAM174A FAM209A HIBADH HSD17B13 KIR2DL3 LMNA LRRC59 NCR3LG1 PEX12 PRSS23 PTGES RETREG3 RNASEK RUNX1 SLC10A1 SLC10A2 SLC10A6 SSMEM1 STX1A TMEM14B TMEM35A TMPRSS2 TMX2 ZDHHC15	19 interacting genes: AGTRAP AQP1 CMTM3 CMTM5 CNIH1 CSNK2A1 EBP EDDM3B MTNR1A NDRG4 PLPP4 SGO1 SNORC TMBIM6 TMEM222 TMEM60 TMEM97 TRAM1L1 TSPO2
Entrez ID		84065	55379
HPRD ID		13167	15181
Ensembl ID		ENSG00000186501	ENSG00000108829
Uniprot IDs		Q9H0R3	Q96AG4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Bile Acid:sodium Symporter Activity Endoplasmic Reticulum Membrane Bile Acid And Bile Salt Transport Endoplasmic Reticulum Protein Binding Positive Regulation Of Granulocyte Differentiation	Membrane Endoplasmic Reticulum Membrane Nuclear Membrane Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Endoplasmic Reticulum Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cholesterol-5,6-oxide Hydrolase Activity Blastocyst Hatching 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity
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