ROPN1L and BEX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ROPN1L	BEX2
Description		rhophilin associated tail protein 1 like	brain expressed X-linked 2
Image			No pdb structure
GO Annotations	Cellular Component	Radial Spoke Extracellular Region Nucleoplasm Cytoplasm Cilium Motile Cilium Cell Projection	Nucleus Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Signaling Receptor Binding Protein Binding Metal Ion Binding Molecular Function Inhibitor Activity
	Biological Process	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Flagellated Sperm Motility Sperm Capacitation	Apoptotic Process Signal Transduction Negative Regulation Of Protein Ubiquitination Regulation Of Apoptotic Process Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Body mass index ( 22446040) Breast cancer ( 21424380) Coronary artery disease in type 1 diabetes ( 29695241) Dermatomyositis or juvenile dermatomyositis ( 26362759) Mean arterial pressure ( 27618448) Triglyceride levels ( 31170924)
Interacting Genes		7 interacting genes: AKAP14 AKAP3 AKAP5 AKAP7 APP BEX2 RSPH3	92 interacting genes: AKAP9 AURKA BCAR3 BLZF1 BORCS6 BRMS1 CCDC197 CCDC57 CCDC85B CCDC88B CDR2 CEP70 COG4 CTAG1A CTAG1B CYSRT1 EXOC8 FGFR2 FSD2 FST GPRASP3 HSF2BP HSPB2 HSPB2-C11orf52 KLHL20 KNSTRN KRT15 KRT19 KRT27 KRT31 KRT34 KRT38 KRT39 KRT40 KRT6A KRT75 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP3-3 KRTAP4-12 KRTAP5-9 KRTAP6-2 KRTAP6-3 LCN2 LDOC1 LMO2 LZTS2 MAGEA11 MAGEA2 MAGEA2B MAGEA4 MDFI MIPOL1 MKRN3 MORN3 MRPL38 MSS51 MTUS2 NECAB2 NFKBID OIP5 OMP PIK3CA PLA2G10 PLEKHG4 PNMA1 PPM1D PRDM14 PTPN11 ROPN1L SERTAD3 SPRED1 SPRY3 SSX2IP SYCE1 TACC3 TRAF1 TRAF2 TRIM27 TRIM42 TRIM69 TRIM73 TRIP6 USHBP1 VHL VPS28 ZDHHC17 ZNF19
Entrez ID		83853	84707
HPRD ID		17986	06484
Ensembl ID		ENSG00000145491	ENSG00000133134
Uniprot IDs		Q96C74	Q9BXY8
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Protein Kinase A Binding Protein Kinase A Regulatory Subunit Binding Positive Regulation Of Long-term Synaptic Potentiation Dendrite Membrane Regulation Of Long-term Synaptic Potentiation Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Calcium-mediated Signaling Cellular Response To CAMP Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Monoatomic Ion Transport Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Metal Ion Transport Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Response To CAMP Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Modulation Of Chemical Synaptic Transmission Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cell Projection Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Endosome To Plasma Membrane Protein Transport Response To Purine-containing Compound Regulation Of Calcium Ion Transmembrane Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Positive Regulation Of Synaptic Transmission Astrocyte Activation Involved In Immune Response Dendritic Spine Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Calcium-mediated Signaling Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Protein Binding Cytoskeleton Organization Supramolecular Fiber Organization Cytosol Morphogenesis Of An Epithelium Hair Follicle Morphogenesis Cytoskeleton Identical Protein Binding Epithelial Cell Differentiation Tissue Morphogenesis Negative Regulation Of Protein Acetylation Microtubule Organizing Center Anatomical Structure Morphogenesis Organelle Organization Keratinization
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