SETD1B

Gene Name		SET domain containing 1B
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome Cytoplasm Nuclear Speck Histone Methyltransferase Complex Set1C/COMPASS Complex
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Histone Methyltransferase Activity (H3-K4 Specific)
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: HIST1H3A HIST1H3E HIST2H3C WDR5
Entrez ID		23067
HPRD ID		19516
Ensembl ID		ENSG00000139718
Uniprot IDs		F6MFW1 Q9UPS6
PDB IDs		3UVO 4ES0
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromatin Silencing At RDNA Chromatin Silencing DNA Methylation Methylation Negative Regulation Of Gene Expression, Epigenetic DNA Modification Gene Silencing DNA Replication-dependent Nucleosome Assembly Regulation Of Gene Expression, Epigenetic Regulation Of Gene Silencing Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Chromatin Organization Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Chromosome Organization DNA Metabolic Process DNA Packaging Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Conformation Change Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gluconeogenesis
Tagcloud ?		11q13 aberrations adam29 ash1l assayed cdkn2a consortium crebbp drinking ep300 escc exome fam135b histopathological kmt2c kmt2d microrna mir548k mll2 mll3 nfe2l2 notch1 oesophageal pik3ca rb1 repertoire sixth tumorigenic vast