CDCA3 and WEE1

Number of citations of the paper that reports this interaction (PMID 12679038)
38

Data Source:
HPRD (in vivo, in vitro)

		CDCA3	WEE1
Gene Name		cell division cycle associated 3	WEE1 G2 checkpoint kinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Molecular_function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Mitotic Nuclear Division Biological_process Protein Ubiquitination Cell Division	G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle Mitotic Nuclear Division Blood Coagulation Peptidyl-tyrosine Phosphorylation Establishment Of Cell Polarity Neuron Projection Morphogenesis Cell Division Regulation Of Cell Cycle
Pathways			G2/M DNA damage checkpoint G2/M Checkpoints G2/M Transition S Phase Cyclin E associated events during G1/S transition Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic Cyclin A/B1 associated events during G2/M transition G1/S Transition Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Cell Cycle Checkpoints Cyclin A:Cdk2-associated events at S phase entry Mitotic G1-G1/S phases Mitotic G2-G2/M phases Polo-like kinase mediated events G2/M DNA replication checkpoint
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APP BCL11A CTDSP1 CTDSP2 CUL1 SKP1 TRAF1 TRAF2 WEE1	21 interactors: BRD8 BRSK1 BRSK2 BTRC CASP3 CDCA3 CDK1 CDK2 CRK CSNK2A1 FBXW11 NEDD4 PIN1 PLK1 SKP2 SMAD3 SMURF1 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		83461	7465
HPRD ID		09670	01907
Ensembl ID		ENSG00000111665	ENSG00000166483
Uniprot IDs		B2R749 F5GX58 Q99618	P30291 Q86V29
PDB IDs			1X8B 2IN6 2IO6 2Z2W 3BI6 3BIZ 3CQE 3CR0
Enriched GO Terms of Interacting Partners?		Cellular Protein Modification Process Positive Regulation Of Proteolysis Cellular Protein Metabolic Process Regulation Of Cell Cycle G2/M Transition Of Mitotic Cell Cycle Notch Signaling Pathway Regulation Of Cellular Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Neuron Differentiation Protein Modification By Small Protein Conjugation Regulation Of Mitotic Cell Cycle Phase Transition Protein Metabolic Process Regulation Of Proteolysis Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Protein Monoubiquitination Positive Regulation Of Catalytic Activity Negative Regulation Of Neurogenesis Negative Regulation Of Cell Development Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Protein Modification Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Apoptotic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Programmed Cell Death Positive Regulation Of Ligase Activity Regulation Of Mitotic Cell Cycle Cell Death Death Regulation Of Protein Phosphorylation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Regulation Of Cell Cycle Process Synaptic Growth At Neuromuscular Junction Regulation Of Catalytic Activity Regulation Of Phosphorylation Regulation Of Neuron Differentiation	G2/M Transition Of Mitotic Cell Cycle Cell Cycle Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cellular Response To Stimulus Mitotic Cell Cycle Cell Communication Positive Regulation Of Intracellular Transport Regulation Of Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Proteasomal Protein Catabolic Process Regulation Of Intracellular Transport Regulation Of Protein Metabolic Process Signaling Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Signal Transduction Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Response To Stimulus Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Apoptotic Signaling Pathway Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cellular Protein Metabolic Process Cellular Protein Catabolic Process Signal Transduction Cellular Macromolecule Catabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Protein Catabolic Process Cellular Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Signal Transduction Regulation Of Cell Cycle Apoptotic Process Regulation Of Establishment Of Protein Localization Programmed Cell Death Regulation Of Cellular Localization Cell Death Death Positive Regulation Of Proteolysis Regulation Of Cellular Component Organization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Localization Positive Regulation Of Mitochondrion Organization Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Tagcloud ?		agilent aifm1 antiproliferative biologically cables2 ccnk cdc25b cdca8 cnnm3 constituents cytometric dmso emge ginseng ginsenosides hepatocarcinoma hepg2 hspa9 ic50 metabolized mu panax ppt primeview rg3 rh1 saponin saponins uqcrc2	arrested associates becomes cascade cdc2 entry g2 hyperphosphorylated immunoprecipitates inactive maintained mapk maturation mpf myt1 oocyte oocytes p34 p90 phosphorylates precise preferentially rsk stock thr14 trigger turn tyr15 xenopus
Tagcloud (Difference) ?		agilent aifm1 antiproliferative biologically cables2 ccnk cdc25b cdca8 cnnm3 constituents cytometric dmso emge ginseng ginsenosides hepatocarcinoma hepg2 hspa9 ic50 metabolized mu panax ppt primeview rg3 rh1 saponin saponins uqcrc2	arrested associates becomes cascade cdc2 entry g2 hyperphosphorylated immunoprecipitates inactive maintained mapk maturation mpf myt1 oocyte oocytes p34 p90 phosphorylates precise preferentially rsk stock thr14 trigger turn tyr15 xenopus
Tagcloud (Intersection) ?