TMEM187 and TAS2R5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM187	TAS2R5
Description		transmembrane protein 187	taste 2 receptor member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Transport Vesicle	Plasma Membrane Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Protein Binding Taste Receptor Activity Bitter Taste Receptor Activity
	Biological Process		Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction G Protein-coupled Receptor Signaling Pathway Chemosensory Behavior Sensory Perception Of Taste
Pathways			G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) Sensory perception of sweet, bitter, and umami (glutamate) taste Sensory perception of sweet, bitter, and umami (glutamate) taste
Drugs
Diseases
GWAS		Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26502338 26663301)	Anorexia nervosa ( 23568457) Late-onset Alzheimer's disease ( 27770636)
Interacting Genes		15 interacting genes: ADRB2 ARL13B CD79A CGRRF1 CISD2 COMT FAM210B GORAB LEUTX MUC1 PGRMC2 SAR1A SPAG4 TAS2R5 TMEM14B	6 interacting genes: CCL4 RTP2 SFT2D2 SLC30A2 TMEM187 VAMP5
Entrez ID		8269	54429
HPRD ID		02086	05453
Ensembl ID		ENSG00000177854	ENSG00000127366
Uniprot IDs		Q14656	A4D1U0 Q502V5 Q9NYW4
PDB IDs
Enriched GO Terms of Interacting Partners?			Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle CCR1 Chemokine Receptor Binding Positive Regulation Of Natural Killer Cell Chemotaxis Zinc:proton Antiporter Activity Zinc Ion Import Into Lysosome Zinc Export Across Plasma Membrane Late Endosome Establishment Of Protein Localization To Membrane Olfactory Receptor Binding CCR5 Chemokine Receptor Binding Vacuolar Transmembrane Transport Zinc Ion Import Into Organelle Secretory Vesicle Endomembrane System
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