PLA2G12A and TMEM37

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		PLA2G12A	TMEM37
Description		phospholipase A2 group XIIA	transmembrane protein 37
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm	Membrane Monoatomic Ion Channel Complex
	Molecular Function	Phospholipase A2 Activity Calcium Ion Binding Protein Binding Hydrolase Activity Metal Ion Binding Calcium-dependent Phospholipase A2 Activity	Voltage-gated Monoatomic Ion Channel Activity Calcium Channel Activity
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Lipid Catabolic Process Arachidonate Secretion	Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs
Diseases
GWAS		HDL cholesterol ( 30275531) Lipoprotein (a) levels ( 33730874) Mean spheric corpuscular volume ( 32888494) Triglycerides ( 30275531)
Interacting Genes		8 interacting genes: DVL2 MEF2C RB1 RPS15 RPS6 TMEM37 UMPS YWHAG	6 interacting genes: HBP1 MPP3 ORM1 PLA2G12A SPIB UBQLN1
Entrez ID		81579	140738
HPRD ID		17858	15536
Ensembl ID		ENSG00000123739	ENSG00000171227
Uniprot IDs		Q542Y6 Q9BZM1	E7EMC0 Q86SV2 Q8WXS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Ribosomal Small Subunit Assembly Cytoplasmic Translation Cell Morphogenesis Involved In Neuron Differentiation Response To Insulin Small Ribosomal Subunit Positive Regulation Of Signal Transduction By P53 Class Mediator Response To Hormone Cytosolic Small Ribosomal Subunit Outflow Tract Morphogenesis Heart Looping Embryonic Heart Tube Morphogenesis Chondrocyte Differentiation Striated Muscle Cell Differentiation Cellular Response To Oxygen-containing Compound Cellular Response To Hormone Stimulus Cellular Response To Xenobiotic Stimulus Sinoatrial Valve Morphogenesis Heart Valve Morphogenesis Negative Regulation Of Protein Kinase Activity Response To Peptide Hormone Ribosomal Small Subunit Biogenesis Translation Orotidine-5'-phosphate Decarboxylase Activity Orotate Phosphoribosyltransferase Activity Intracellular Signal Transduction Negative Regulation Of Kinase Activity TOR Signaling Muscle Cell Fate Determination Nephron Tubule Epithelial Cell Differentiation Cellular Response To Trichostatin A Cellular Response To Insulin Stimulus Cytosolic Ribosome Positive Regulation Of Intracellular Signal Transduction Muscle Cell Differentiation Negative Regulation Of Protein Phosphorylation Epithelial Tube Morphogenesis Convergent Extension Involved In Neural Plate Elongation Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Macrophage Apoptotic Process Primary Heart Field Specification Glomerulus Morphogenesis Negative Regulation Of Phosphorylation Chromatin Lock Complex 'de Novo' UMP Biosynthetic Process Protein Kinase C Inhibitor Activity Osteoblast Differentiation Cytosol Regulation Of Synaptic Activity Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion
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