TMEM37 and SPIB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TMEM37	SPIB
Gene Name		transmembrane protein 37	Spi-B transcription factor (Spi-1/PU.1 related)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Cytoplasm
	Molecular Function	Voltage-gated Ion Channel Activity Calcium Channel Activity	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Regulation Of Ion Transmembrane Transport Calcium Ion Transmembrane Transport	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Primary biliary cirrhosis ( 21399635 20639880)
Protein-Protein Interactions		6 interactors: HBP1 MPP3 ORM1 PLA2G12A SPIB UBQLN1	19 interactors: CEBPB CREBBP CSNK2A1 CSNK2A2 E2F1 E2F2 E2F3 E2F4 EP300 GATA1 IRF4 JUN MAPK3 MAPK8 RB1 SPI1 SSB TBP TMEM37
Entrez ID		140738	6689
HPRD ID		15536	06007
Ensembl ID		ENSG00000171227	ENSG00000269404
Uniprot IDs		E7EMC0 Q86SV2 Q8WXS4	Q01892
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Chylomicron Remnant Clearance	Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Apoptotic Process Programmed Cell Death Cell Death Nitrogen Compound Metabolic Process Death Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Regulation Of Chromosome Organization DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Binding Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Binding Myeloid Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Immune System Process
Tagcloud ?			abc amplify attractive augmenting btk card11 cereblon dlbcl dlbcls downregulates fashion ibrutinib ifnbeta inspire irf4 irf7 killing kills lenalidomide lethal lymphomas myd88 owing prosurvival repressing sparing synergizes synthetically transactivating
Tagcloud (Difference) ?			abc amplify attractive augmenting btk card11 cereblon dlbcl dlbcls downregulates fashion ibrutinib ifnbeta inspire irf4 irf7 killing kills lenalidomide lethal lymphomas myd88 owing prosurvival repressing sparing synergizes synthetically transactivating
Tagcloud (Intersection) ?