TRIM11 and RNF126

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		TRIM11	RNF126
Gene Name		tripartite motif containing 11	ring finger protein 126
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Ligase Activity Protein Domain Specific Binding	Epidermal Growth Factor Receptor Binding Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Neurogenesis Defense Response To Virus Negative Regulation Of Viral Release From Host Cell	Protein Monoubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Proliferation Retrograde Transport, Endosome To Golgi Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: MED15 PAX6 RNF126 TRIM27 TRIM29 TRIM35	26 interactors: AICDA BAG6 CDKN1A CSNK2B EGFR HMGCL MDM2 NUDT3 OTUB1 OTUB2 PLK1 PSMF1 RBX1 SNUPN TRIM11 TRIM23 TRIM26 TRIM52 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N USP15 USP2
Entrez ID		81559	55658
HPRD ID		07429	11501
Ensembl ID		ENSG00000154370	ENSG00000070423
Uniprot IDs		Q96F44	A8K0Q1 Q9BV68
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Release From Host Cell Regulation Of Viral Release From Host Cell Protein K63-linked Ubiquitination Retrograde Transport, Endosome To Golgi Negative Regulation Of Viral Process Pancreatic A Cell Development Forebrain-midbrain Boundary Formation Regulation Of Transcription From RNA Polymerase II Promoter Involved In Somatic Motor Neuron Fate Commitment Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Glucagon Secretion Regulation Of Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere Morphogenesis Protein Polyubiquitination Transcription From RNA Polymerase II Promoter Regulation Of Asymmetric Cell Division Regulation Of Transcription From RNA Polymerase II Promoter Involved In Spinal Cord Motor Neuron Fate Specification Positive Regulation Of Cell Fate Specification Transcription, DNA-templated Endosomal Transport Regulation Of Transcription From RNA Polymerase II Promoter Involved In Ventral Spinal Cord Interneuron Specification RNA Biosynthetic Process Pancreatic A Cell Differentiation Negative Regulation Of Calcium Ion Import Somatic Motor Neuron Differentiation Regulation Of Cellular Localization Stem Cell Development Forebrain Anterior/posterior Pattern Specification Cerebral Cortex Regionalization Negative Regulation Of Transcription, DNA-templated Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Forebrain Dorsal/ventral Pattern Formation Regulation Of Glucagon Secretion Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Interferon-gamma Secretion Oligodendrocyte Cell Fate Specification Lacrimal Gland Development Iris Morphogenesis Cornea Development In Camera-type Eye Rhombomere Development Stem Cell Differentiation Insulin Metabolic Process Negative Regulation Of Protein Phosphorylation Formation Of Anatomical Boundary Cellular Response To Prostaglandin E Stimulus	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Catabolic Process Proteolysis Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Polyubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein K48-linked Ubiquitination Immune System Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Cellular Response To Oxygen Levels Regulation Of Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Cellular Response To Stress Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Cell Cycle Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Mitotic Cell Cycle Phase Transition Immune Response-regulating Signaling Pathway Immune Response Positive Regulation Of Cell Cycle Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Mitotic Cell Cycle Checkpoint Regulation Of Gene Expression Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity
Tagcloud ?		adaptor antiviral cc cc2 collectively constitutively conversely defense dimerization ectopic ifnalpha ifnbeta infectivity innate interacted interferons irf3 knockdown mavs nap1 opposite phosphorylates rig sintbad tank tbk1 tightly traf tripartite	cargo cathepsin cation cholera depleted dispersed e3 endosomal endosomes finger furin internalization lastly ligase lysosomal mannose missorting mpr proteasome rab4 rescue retrograde route sorting tgn38 toxin transiently ubiquitin unaffected
Tagcloud (Difference) ?		adaptor antiviral cc cc2 collectively constitutively conversely defense dimerization ectopic ifnalpha ifnbeta infectivity innate interacted interferons irf3 knockdown mavs nap1 opposite phosphorylates rig sintbad tank tbk1 tightly traf tripartite	cargo cathepsin cation cholera depleted dispersed e3 endosomal endosomes finger furin internalization lastly ligase lysosomal mannose missorting mpr proteasome rab4 rescue retrograde route sorting tgn38 toxin transiently ubiquitin unaffected
Tagcloud (Intersection) ?