TRIM11 and TRIM29

Number of citations of the paper that reports this interaction (PubMedID 11331580)
63

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIM11	TRIM29
Description		tripartite motif containing 11	tripartite motif containing 29
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Lysosome Adherens Junction
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Viral Transcription Suppression Of Viral Release By Host Innate Immune Response Negative Regulation Of DNA-templated Transcription Host-mediated Suppression Of Symbiont Invasion Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Neurogenesis Defense Response To Virus Protein Autoubiquitination Negative Regulation Of AIM2 Inflammasome Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Immune System Process Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Interferon gamma signaling
Drugs
Diseases
GWAS		Hip circumference (psychosocial stress interaction) ( 25271088) Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433)	Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)
Interacting Genes		14 interacting genes: KDM5C MAPT MCL1 MECOM MED15 OGT PAX6 PHLPP1 RNF126 TRIM27 TRIM29 TRIM35 UBE2D2 USP14	55 interacting genes: ACTN3 ANKS1A ATM CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF13 RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM
Entrez ID		81559	23650
HPRD ID		07429	10280
Ensembl ID		ENSG00000154370	ENSG00000137699
Uniprot IDs		Q96F44	B7Z5V5 B7Z8U9 E9PRL4 Q14134
PDB IDs		7QS1	2CSV
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Metabolic Process Suppression Of Viral Release By Host Negative Regulation Of DNA-templated Transcription Nucleus Negative Regulation Of Macromolecule Metabolic Process Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Cytosol Response To Stress Regulation Of Protein Localization To Synapse Negative Regulation Of Catabolic Process Post-translational Protein Modification Ubiquitin Protein Ligase Activity Negative Regulation Of RNA Metabolic Process Apoptotic Process Cell Fate Determination Cell Death Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasm Programmed Cell Death Histone-dependent DNA Binding Tubulin Complex Microtubule Lateral Binding Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Regulation Of Primary Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Protein Modification Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Polyubiquitination Innate Immune Response Transferase Activity Chromatin Remodeling Neurofibrillary Tangle Assembly Protein K63-linked Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process BH Domain Binding Chromatin DNA Binding Habenula Development Pallium Development Protein O-acetylglucosaminyltransferase Activity Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System	Negative Regulation Of Viral Transcription Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-protein Transferase Activity Nucleus Cytoskeleton Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Viral Transcription Regulation Of Skeletal Muscle Fiber Development Protein Ubiquitination Positive Regulation Of DNA Recombination Cytosol Positive Regulation Of Metabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Development Somatic Cell DNA Recombination Cytoplasm Ubiquitin Protein Ligase Activity Positive Regulation Of Autophagy Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA Recombination Signal Transduction By P53 Class Mediator Suppression Of Viral Release By Host Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Ligase Complex Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Intracellular Signal Transduction Double-strand Break Repair Via Nonhomologous End Joining Nucleoplasm Protein Modification Process Guanine/thymine Mispair Binding Positive Regulation Of Biosynthetic Process Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Positive Regulation Of Catabolic Process Protein Localization To Site Of Double-strand Break Positive Regulation Of Cell Development Regulation Of DNA Recombination Somatic Diversification Of Immunoglobulins Involved In Immune Response Regulation Of RNA Metabolic Process Negative Regulation Of Viral Process Macromolecule Catabolic Process Identical Protein Binding Protein Binding Signal Transduction In Response To DNA Damage Transcription Regulator Complex Positive Regulation Of Isotype Switching To IgA Isotypes
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