STK38 and MOB2

Number of citations of the paper that reports this interaction (PubMedID 15067004)
0

Data Source:
HPRD (in vitro, in vivo)

		STK38	MOB2
Description		serine/threonine kinase 38	MOB kinase activator 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm Cytosol Site Of Double-strand Break Glutamatergic Synapse	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Cadherin Binding Metal Ion Binding Protein Serine Kinase Activity Ubiquitin-like Protein Reader Activity Histone Reader Activity UFM1-modified Protein Reader Activity	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	DNA Damage Checkpoint Signaling Chromatin Organization Protein Phosphorylation DNA Damage Response Negative Regulation Of Metabolic Process Intracellular Signal Transduction Protein Modification Process Negative Regulation Of MAP Kinase Activity Postsynapse Organization	Signal Transduction
Pathways		RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
Drugs		Fostamatinib
Diseases
GWAS		Mean platelet volume ( 32888494) Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) ( 28521775) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Brain morphology (MOSTest) ( 32665545) Myocardial infarction ( 33532862) Prostate cancer ( 29892016) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: BANP CALM1 CTDP1 H2AC20 H2BC21 H3C6 HERC5 HRAS MOB2 S100B SENP2 TRAF3 TRIM14 TRIM25 YWHAB YWHAZ	11 interacting genes: ATG3 CCDC90B FAAP20 FRA10AC1 MIIP NDRG2 NTAQ1 OR5H1 RETREG3 SFT2D2 STK38
Entrez ID		11329	81532
HPRD ID		09511	17581
Ensembl ID		ENSG00000112079	ENSG00000182208
Uniprot IDs		Q15208	Q70IA6
PDB IDs		1PSB 6BXI
Enriched GO Terms of Interacting Partners?		Defense Response To Other Organism Innate Immune Response Phosphoserine Residue Binding Response To Other Organism Defense Response To Symbiont Nucleus Immune Response Structural Constituent Of Chromatin Response To External Biotic Stimulus Defense Response Nucleoplasm Cadherin Binding Nucleosome Ubiquitin Protein Ligase Activity Perinuclear Region Of Cytoplasm Protein Sequestering Activity Regulation Of Synaptic Plasticity Immune System Process Negative Regulation Of Protein Localization To Nucleus Long-term Synaptic Potentiation Cytoplasm Regulation Of Neuronal Synaptic Plasticity MRNA Transcription Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity GTPase Complex Regulation Of Defense Response To Virus Ubiquitin-protein Transferase Activity Synaptic Target Recognition TFIIF-class Transcription Factor Complex Binding PKR/eIFalpha Signaling Defense Response To Virus Calcium-dependent Protein Binding Cytosol Antiviral Innate Immune Response Protein Modification Process
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