EGFL8 and RMDN3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EGFL8	RMDN3
Gene Name		EGF-like-domain, multiple 8	regulator of microtubule dynamics 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Spindle Pole Nucleus Mitochondrion Mitochondrial Outer Membrane Microtubule Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding	Protein Binding
	Biological Process	In Utero Embryonic Development	Cellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Oleic acid (18:1n-9) plasma levels ( 23362303) Prostate cancer ( 23535732)
Protein-Protein Interactions		3 interactors: KRTAP10-3 RMDN3 TIMM8B	6 interactors: EGFL8 PSEN1 VAPA YWHAB YWHAG YWHAZ
Entrez ID		80864	55177
HPRD ID		16854	07687
Ensembl ID		ENSG00000241404	ENSG00000137824
Uniprot IDs		Q99944	Q96TC7
PDB IDs
Enriched GO Terms of Interacting Partners?		Chaperone-mediated Protein Transport	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Cell Death Death Positive Regulation Of Signal Transduction Regulation Of Mitochondrion Organization Intracellular Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Protein Localization Establishment Of Localization In Cell Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Membrane Organization Positive Regulation Of Intracellular Transport Cellular Localization Apoptotic Process Programmed Cell Death Regulation Of Signal Transduction Apoptotic Signaling Pathway Regulation Of Signaling Positive Regulation Of Organelle Organization Cellular Protein Localization Protein Targeting Protein Transport Regulation Of Intracellular Transport Ammonium Transport Activation Of MAPKK Activity Regulation Of Apoptotic Process Establishment Of Protein Localization Regulation Of Cell Death Generation Of Neurons Neurogenesis Intracellular Signal Transduction Cajal-Retzius Cell Differentiation Beta-amyloid Formation Regulation Of Cellular Component Organization Regulation Of Establishment Of Protein Localization Regulation Of Protein Kinase Activity Positive Regulation Of Transport Regulation Of Kinase Activity Regulation Of Protein Localization Mitochondrial Transport Positive Regulation Of Intracellular Signal Transduction Leukocyte Activation Involved In Immune Response Negative Regulation Of Cellular Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
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