UBXN6 and SUSD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBXN6	SUSD6
Description		UBX domain protein 6	sushi domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Lysosomal Membrane Endosome Centrosome Cytosol Cytoskeleton Membrane Early Endosome Membrane Late Endosome Membrane Protein-containing Complex Extracellular Exosome	Membrane
	Molecular Function	Protein Binding ATPase Binding	Protein Binding
	Biological Process	Response To Stress Macroautophagy Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway ERAD Pathway	DNA Damage Response
Pathways
Drugs
Diseases
GWAS		Delta-5 desaturase activity response to n3-polyunsaturated fat supplement ( 29246731) Multiple sclerosis ( 31604244) Red blood cell count ( 32888494)
Interacting Genes		21 interacting genes: APP DAZAP2 DERL1 FAM168A GSK3B MAGEA4 MCL1 NLGN3 OGT PLEKHB2 SMURF1 SUSD6 SVIP TNFAIP3 TRIM39 UBC UBXN10 UBXN2A UBXN2B VCP YOD1	9 interacting genes: ADAMTSL4 DCUN1D1 FAM241B KRTAP1-3 KRTAP10-8 MTURN OTULIN TMEM19 UBXN6
Entrez ID		80700	9766
HPRD ID		18253	10010
Ensembl ID		ENSG00000167671	ENSG00000100647
Uniprot IDs		Q9BZV1	Q92537
PDB IDs		6SAP 8FCL 8FCM 8FCN 8FCO 8FCP 8FCQ 8FCR 8FCT
Enriched GO Terms of Interacting Partners?		Regulation Of Proteolysis Regulation Of Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Proteolysis Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Protein Localization Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Protein Catabolic Process Regulation Of Post-translational Protein Modification Negative Regulation Of Proteolysis Ubiquitin Protein Ligase Binding Macromolecule Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process ERAD Pathway Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin Binding Regulation Of Protein Modification Process Response To Endoplasmic Reticulum Stress Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of ERAD Pathway Catabolic Process Derlin-1 Retrotranslocation Complex Regulation Of Extrinsic Apoptotic Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stress Membrane Assembly Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Protein Metabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Protein Localization Endoplasmic Reticulum Unfolded Protein Response Protein K11-linked Deubiquitination Cellular Response To Misfolded Protein Positive Regulation Of Neuron Apoptotic Process Regulation Of Apoptotic Signaling Pathway	Pigment Cell Development Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of NF-kappaB Transcription Factor Activity
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