FOSL1 and USF1

Number of citations of the paper that reports this interaction (PMID 9160889)
6

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid, in vitro, in vivo)

		FOSL1	USF1
Gene Name		FOS-like antigen 1	upstream transcription factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Presynaptic Membrane Neuron Projection	Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Double-stranded DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Enzyme Binding Protein Kinase Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	In Utero Embryonic Development Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Chemotaxis Cellular Defense Response Vitellogenesis Female Pregnancy Learning Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Response To Mechanical Stimulus Response To Virus Response To Gravity Cellular Response To Extracellular Stimulus Response To Progesterone Response To Cytokine Response To Drug Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Corticosterone Response To CAMP Placenta Blood Vessel Development	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Hypoxia Glucose Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Response To UV Late Viral Transcription Cellular Response To Insulin Stimulus Glucose Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Carbon Catabolite Regulation Of Transcription Negative Regulation Of Fibrinolysis Lipid Homeostasis
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		23 interactors: ATF2 ATF3 ATF4 ATXN1 CALCOCO1 CEBPA CEBPE CEBPG CREB5 DDIT3 EP300 JUN JUNB KPNA1 LDOC1 MAF MAFB NME7 PARVG TAB2 TRIM24 USF1 WFDC1	13 interactors: APP ESR1 FOS FOSL1 GTF2I HDAC9 NFYA PPRC1 PRKDC TCF3 TCFL5 TRAF2 USF2
Entrez ID		8061	7391
HPRD ID		00643	01880
Ensembl ID		ENSG00000175592	ENSG00000158773
Uniprot IDs		B4DR11 E9PPX2 P15407	P22415
PDB IDs			1AN4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Gene Expression Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Organ Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Organic Substance Response To Endoplasmic Reticulum Stress Negative Regulation Of Nucleic Acid-templated Transcription System Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of RNA Biosynthetic Process Leukocyte Differentiation Response To Organic Substance Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Biosynthetic Process Cellular Response To Unfolded Protein Multicellular Organismal Development Regulation Of Cellular Process ER-nucleus Signaling Pathway Myeloid Cell Differentiation Cellular Response To Topologically Incorrect Protein Anatomical Structure Development Myeloid Leukocyte Differentiation Negative Regulation Of Transcription, DNA-templated	Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Immunoglobulin V(D)J Recombination B Cell Lineage Commitment Positive Regulation Of Metabolic Process Cellular Metabolic Process Biosynthetic Process B Cell Differentiation Response To Gravity Reproductive Process Defense Response Organ Development Learning Response To Oxidative Stress B Cell Activation Regulation Of Stem Cell Maintenance V(D)J Recombination Cell Communication Regulation Of Cell Differentiation Response To Hormone Regulation Of Cellular Process Response To Organic Substance Somatic Recombination Of Immunoglobulin Gene Segments Response To Corticosterone
Tagcloud ?		associations blotting ccnd1 ccnd2 dab2 dact1 day detect displayed expressions increasing jun mean pathway pcr placenta play promoting real relationship signaling spss target tissue tissues trend value western wnt	affective bdnf bisulfite choline dams epigenetically explicate formerly g11 g18 hdac1 id impairments iron methylations modifies neurotrophic pnd pnd15 pnd65 pnd7 postnatal prompt pups repletion revealing reverses span supplementation
Tagcloud (Difference) ?		associations blotting ccnd1 ccnd2 dab2 dact1 day detect displayed expressions increasing jun mean pathway pcr placenta play promoting real relationship signaling spss target tissue tissues trend value western wnt	affective bdnf bisulfite choline dams epigenetically explicate formerly g11 g18 hdac1 id impairments iron methylations modifies neurotrophic pnd pnd15 pnd65 pnd7 postnatal prompt pups repletion revealing reverses span supplementation
Tagcloud (Intersection) ?