FOSL1 and BATF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FOSL1	BATF3
Description		FOS like 1, AP-1 transcription factor subunit	basic leucine zipper ATF-like transcription factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding Promoter-specific Chromatin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	In Utero Embryonic Development Toll-like Receptor Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Chemotaxis Inflammatory Response Cellular Defense Response Vitellogenesis Positive Regulation Of Cell Population Proliferation Response To Wounding Response To Virus Gene Expression Cytokine-mediated Signaling Pathway Placenta Blood Vessel Development Integrated Stress Response Signaling Positive Regulation Of MiRNA Transcription Positive Regulation Of DNA-templated Transcription Initiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Virus Myeloid Dendritic Cell Differentiation Dendritic Cell Differentiation Integrated Stress Response Signaling
Pathways		NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 27863252 32888494) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 23128233) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252)	Asthma ( 32296059) Leprosy ( 25642632) Multiple sclerosis ( 31604244) Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232) ( 29923122) Type 1 diabetes ( 34012112)
Interacting Genes		30 interacting genes: ABL1 ATF3 ATF4 ATXN1 BATF3 CALCOCO1 CCDC120 CEBPA CEBPE CEBPG CREB5 DDIT3 DNMT3L EP300 ERCC6 GCC1 JUN JUNB KIFC3 KPNA1 LDOC1 MAF MAFB NME7 PARVG PIN1 TAB2 TRIM24 USF1 WFDC1	21 interacting genes: AGXT APPL1 ATF3 ATF4 BACH2 BATF CEBPA CEBPE CEBPG CRK DBP DDIT3 EPAS1 FOSL1 GPATCH2L MAFF MAFG NFATC2IP PGR RHOXF2 STAT3
Entrez ID		8061	55509
HPRD ID		00643	18081
Ensembl ID		ENSG00000175592	ENSG00000123685
Uniprot IDs		A0A0S2Z595 E9PKL5 E9PPX2 P15407	Q9NR55
PDB IDs
Enriched GO Terms of Interacting Partners?		Integrated Stress Response Signaling RNA Polymerase II Transcription Regulator Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Intracellular Signaling Cassette Positive Regulation Of Transcription By RNA Polymerase II Chromatin Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Intracellular Signal Transduction Positive Regulation Of Metabolic Process DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Regulator Complex Regulation Of RNA Metabolic Process Myeloid Cell Differentiation Leukocyte Differentiation DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cellular Response To Stress Regulation Of Primary Metabolic Process DNA-templated Transcription Positive Regulation Of Gene Expression Mononuclear Cell Differentiation Sequence-specific DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Animal Organ Development Regulation Of Gene Expression Signal Transduction Identical Protein Binding Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Response To Stress Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Response To Nutrient Levels Negative Regulation Of Macromolecule Metabolic Process Nucleobase-containing Compound Biosynthetic Process Developmental Process	RNA Polymerase II Transcription Regulator Complex DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Integrated Stress Response Signaling Chromatin Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Identical Protein Binding Regulation Of Metabolic Process CHOP-ATF3 Complex CHOP-ATF4 Complex RNA Polymerase II-specific DNA-binding Transcription Factor Binding Epithelial Cell Maturation RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Intracellular Signaling Cassette CHOP-C/EBP Complex Transcription Regulator Complex DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Myeloid Cell Differentiation Transcription Cis-regulatory Region Binding Developmental Process GDF15-GFRAL Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Cytokine Production MRNA Transcription By RNA Polymerase II Cellular Developmental Process
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