USF1 and USF2

Number of citations of the paper that reports this interaction (PMID 8576131)
45

Data Source:
HPRD (in vitro, in vivo)

		USF1	USF2
Gene Name		upstream transcription factor 1	upstream transcription factor 2, c-fos interacting
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex	Nucleus Nucleoplasm
	Molecular Function	Double-stranded DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Enzyme Binding Protein Kinase Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Hypoxia Glucose Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Response To UV Late Viral Transcription Cellular Response To Insulin Stimulus Glucose Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Carbon Catabolite Regulation Of Transcription Negative Regulation Of Fibrinolysis Lipid Homeostasis	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Transcription From RNA Polymerase II Promoter Lactation Late Viral Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Lipid Homeostasis
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		13 interactors: APP ESR1 FOS FOSL1 GTF2I HDAC9 NFYA PPRC1 PRKDC TCF3 TCFL5 TRAF2 USF2	11 interactors: BRCA1 EP300 FOS LZTS2 MAF NFYA PPARGC1A PPRC1 RELA TEAD2 USF1
Entrez ID		7391	7392
HPRD ID		01880	02668
Ensembl ID		ENSG00000158773	ENSG00000105698
Uniprot IDs		P22415	Q15853
PDB IDs		1AN4
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Immunoglobulin V(D)J Recombination B Cell Lineage Commitment Positive Regulation Of Metabolic Process Cellular Metabolic Process Biosynthetic Process B Cell Differentiation Response To Gravity Reproductive Process Defense Response Organ Development Learning Response To Oxidative Stress B Cell Activation Regulation Of Stem Cell Maintenance V(D)J Recombination Cell Communication Regulation Of Cell Differentiation Response To Hormone Regulation Of Cellular Process Response To Organic Substance Somatic Recombination Of Immunoglobulin Gene Segments Response To Corticosterone	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Transcription, DNA-templated Positive Regulation Of Metabolic Process RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Response To Hormone Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Abiotic Stimulus Nitrogen Compound Metabolic Process Cellular Response To Tumor Necrosis Factor Response To Organonitrogen Compound Response To Lipid Response To Tumor Necrosis Factor Response To Organic Cyclic Compound Positive Regulation Of Histone Acetylation Response To Radiation Positive Regulation Of Peptidyl-lysine Acetylation Response To Extracellular Stimulus Positive Regulation Of Protein Acetylation Response To Steroid Hormone Regulation Of Metabolic Process Cellular Response To Organic Substance Response To Temperature Stimulus Intracellular Receptor Signaling Pathway Cellular Response To Oxidative Stress Cellular Response To Hormone Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Androgen Receptor Signaling Pathway
Tagcloud ?		affective bdnf bisulfite choline dams epigenetically explicate formerly g11 g18 hdac1 id impairments iron methylations modifies neurotrophic pnd pnd15 pnd65 pnd7 postnatal prompt pups repletion revealing reverses span supplementation	anomalies behind bioinformatics cart ctf dependence depicting ebpbeta elaborate govern instance intron likewise modify nfya nutshell oprk1 pdyn pdyns pharmaceutical prodynorphin prompting regimes retrieve snps tbp vdr vulnerability
Tagcloud (Difference) ?		affective bdnf bisulfite choline dams epigenetically explicate formerly g11 g18 hdac1 id impairments iron methylations modifies neurotrophic pnd pnd15 pnd65 pnd7 postnatal prompt pups repletion revealing reverses span supplementation	anomalies behind bioinformatics cart ctf dependence depicting ebpbeta elaborate govern instance intron likewise modify nfya nutshell oprk1 pdyn pdyns pharmaceutical prodynorphin prompting regimes retrieve snps tbp vdr vulnerability
Tagcloud (Intersection) ?