WDR82 and TOX4

Number of citations of the paper that reports this interaction (PubMedID 20516061)
59

Data Source:
BioGRID (affinity chromatography technology, pull down)

		WDR82	TOX4
Description		WD repeat domain 82	TOX high mobility group box family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Histone Methyltransferase Complex Set1C/COMPASS Complex PTW/PP1 Phosphatase Complex	Chromosome, Telomeric Region Chromatin Nucleus Chromosome PTW/PP1 Phosphatase Complex
	Molecular Function	Chromatin Binding Protein Binding LncRNA Binding	DNA Binding Protein Binding Chromatin DNA Binding
	Biological Process	RNA Polymerase II Promoter Clearance DNA-templated Transcription Termination Gene Expression Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Elongation By RNA Polymerase II Nuclear RNA Surveillance LncRNA Catabolic Process Negative Regulation Of LncRNA Transcription	RNA Polymerase II Promoter Clearance Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Transcription Elongation By RNA Polymerase II
Pathways		Formation of WDR5-containing histone-modifying complexes Nuclear RNA decay
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) General cognitive ability ( 29844566) Schizophrenia ( 23974872) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		9 interacting genes: CEBPA EP300 NAGK OSGEP PPP1CA PPP1R10 SETD1B TOX4 TP53	16 interacting genes: ATXN1 BANP CCBE1 CREB1 EXOSC10 FNDC3B GEMIN6 HIPK3 HSPB1 MYL7 PPP1CA QRICH1 TBX6 WDR82 ZMYND19 ZNF512B
Entrez ID		80335	9878
HPRD ID		15183	12661
Ensembl ID		ENSG00000164091	ENSG00000092203
Uniprot IDs		Q6UXN9	O94842
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Promoter Clearance PTW/PP1 Phosphatase Complex Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled DNA-templated Transcription Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Carbohydrate Catabolic Process Protein Stabilization Positive Regulation Of DNA-templated Transcription, Elongation Nucleic Acid Metabolic Process Chromatin DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Generation Of Precursor Metabolites And Energy STAT Family Protein Binding Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Glucose Metabolic Process Lung Development Regulation Of DNA-templated Transcription Elongation Macromolecule Biosynthetic Process Regulation Of Protein Stability Carbohydrate Metabolic Process Circadian Rhythm Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription Elongation By RNA Polymerase II Protein Phosphatase 1 Binding Negative Regulation Of Stem Cell Proliferation Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription, Elongation Chromosome, Telomeric Region Photoperiodism Entrainment Of Circadian Clock Chromatin RNA Polymerase II-specific DNA-binding Transcription Factor Binding T Cell Lineage Commitment Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein-containing Complex Disassembly Transcription Regulator Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Macromolecule Metabolic Process Chromosome Somitogenesis	RNA Polymerase II Promoter Clearance PTW/PP1 Phosphatase Complex RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription, Elongation DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Glial Cell Proliferation Chemotaxis To Arachidonate RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Protein Kinase C Signaling RNA Surveillance Nuclear RNA Surveillance Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Metabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Transforming Growth Factor Beta3 Production Visual Behavior Nucleic Acid Metabolic Process Visual Learning Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Transcription Euchromatin RNA Binding Nuclear Polyadenylation-dependent SnoRNA Catabolic Process Nuclear Polyadenylation-dependent SnRNA Catabolic Process Nuclear Polyadenylation-dependent CUT Catabolic Process Positive Regulation Of DNA-templated Transcription, Elongation RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Transcription Elongation By RNA Polymerase II LncRNA Catabolic Process Negative Regulation Of LncRNA Transcription MRNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleus Transcription By RNA Polymerase II Response To Dehydroepiandrosterone Positive Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process
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