WDR82

Description		WD repeat domain 82
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Histone Methyltransferase Complex Set1C/COMPASS Complex PTW/PP1 Phosphatase Complex
	Molecular Function	Chromatin Binding Protein Binding LncRNA Binding
	Biological Process	RNA Polymerase II Promoter Clearance DNA-templated Transcription Termination Gene Expression Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Elongation By RNA Polymerase II Nuclear RNA Surveillance LncRNA Catabolic Process Negative Regulation Of LncRNA Transcription
Pathways		Formation of WDR5-containing histone-modifying complexes Nuclear RNA decay
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) General cognitive ability ( 29844566) Schizophrenia ( 23974872) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		9 interacting genes: CEBPA EP300 NAGK OSGEP PPP1CA PPP1R10 SETD1B TOX4 TP53
Entrez ID		80335
HPRD ID		15183
Ensembl ID		ENSG00000164091
Uniprot IDs		Q6UXN9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Promoter Clearance PTW/PP1 Phosphatase Complex Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled DNA-templated Transcription Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Carbohydrate Catabolic Process Protein Stabilization Positive Regulation Of DNA-templated Transcription, Elongation Nucleic Acid Metabolic Process Chromatin DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Generation Of Precursor Metabolites And Energy STAT Family Protein Binding Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Glucose Metabolic Process Lung Development Regulation Of DNA-templated Transcription Elongation Macromolecule Biosynthetic Process Regulation Of Protein Stability Carbohydrate Metabolic Process Circadian Rhythm Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription Elongation By RNA Polymerase II Protein Phosphatase 1 Binding Negative Regulation Of Stem Cell Proliferation Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription, Elongation Chromosome, Telomeric Region Photoperiodism Entrainment Of Circadian Clock Chromatin RNA Polymerase II-specific DNA-binding Transcription Factor Binding T Cell Lineage Commitment Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein-containing Complex Disassembly Transcription Regulator Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Macromolecule Metabolic Process Chromosome Somitogenesis
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