FUZ and RSG1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		FUZ	RSG1
Gene Name		fuzzy planar cell polarity protein	REM2 and RAB-like small GTPase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Ciliary Basal Body
	Molecular Function		GTP Binding
	Biological Process	Establishment Of Planar Polarity Neural Tube Closure Hair Follicle Development Negative Regulation Of Cell Proliferation Regulation Of Smoothened Signaling Pathway Embryonic Body Morphogenesis Protein Transport Spinal Cord Dorsal/ventral Patterning Negative Regulation Of Cell Migration Nonmotile Primary Cilium Assembly Cilium Assembly Positive Regulation Of Cilium Assembly Embryonic Skeletal System Morphogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Neural Crest Formation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation	Exocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Exocytosis Regulation Of Vesicle Fusion Cellular Protein Localization Cilium Assembly
Pathways		Hedgehog 'off' state Signaling by Hedgehog
Drugs
Diseases
GWAS			Liver enzyme levels (gamma-glutamyl transferase) ( 22001757)
Protein-Protein Interactions		1 interactors: RSG1	4 interactors: FUZ IMPDH2 MSLN TMEM14C
Entrez ID		80199	79363
HPRD ID		08662	14399
Ensembl ID		ENSG00000010361	ENSG00000132881
Uniprot IDs		Q9BT04	Q9BU20
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Neural Crest Formation Positive Regulation Of Cilium Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation GMP Biosynthetic Process GMP Metabolic Process
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