FUZ and CPLANE2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		FUZ	CPLANE2
Description		fuzzy planar cell polarity protein	ciliogenesis and planar polarity effector complex subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Cell Projection Extracellular Exosome	Cytoplasm Centriole Cytoskeleton Cilium Ciliary Transition Zone Ciliary Basal Body Cell Projection Ciliary Base
	Molecular Function	Protein Binding Phosphatidylinositol Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Establishment Of Planar Polarity Neural Tube Closure Hair Follicle Development Negative Regulation Of Cell Population Proliferation Regulation Of Smoothened Signaling Pathway Embryonic Body Morphogenesis Protein Transport Vesicle-mediated Transport Neural Tube Development Cell Projection Organization Negative Regulation Of Cell Migration Intraciliary Transport Positive Regulation Of Cilium Assembly Embryonic Skeletal System Morphogenesis Cilium Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Neural Crest Formation Regulation Of Cilium Assembly Non-motile Cilium Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation	Endocardial Cushion Fusion Exocytosis Smoothened Signaling Pathway Intracellular Protein Localization Regulation Of Smoothened Signaling Pathway Protein Transport Protein Processing Regulation Of Exocytosis Cell Projection Organization Regulation Of Vesicle Fusion Axoneme Assembly Limb Development Cilium Assembly Cranial Skeletal System Development
Pathways		Hedgehog 'off' state
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: CPLANE2 DSCR9	5 interacting genes: FUZ IMPDH2 MSLN RND3 TMEM14C
Entrez ID		80199	79363
HPRD ID		08662	14399
Ensembl ID		ENSG00000010361	ENSG00000132881
Uniprot IDs		E9PK12 Q9BT04	Q9BU20
PDB IDs		7Q3D
Enriched GO Terms of Interacting Partners?		Regulation Of Antibacterial Peptide Production Positive Regulation Of Antibacterial Peptide Production Protein Maturation Epidermal Lamellar Body Positive Regulation Of Antimicrobial Peptide Production Cell Adhesion Involved In Heart Morphogenesis Endocardial Cushion Fusion Positive Regulation Of Antimicrobial Humoral Response Positive Regulation Of Defense Response To Bacterium Regulation Of Antimicrobial Humoral Response Regulation Of Defense Response To Bacterium Cranial Skeletal System Development Positive Regulation Of Humoral Immune Response	IMP Dehydrogenase Activity Regulation Of Heme Biosynthetic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Negative Regulation Of Neural Crest Formation
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