ELOVL7 and ADGRE2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ELOVL7	ADGRE2
Description		ELOVL fatty acid elongase 7	adhesion G protein-coupled receptor E2
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane Leading Edge Membrane Ruffle Membrane Cell Projection
	Molecular Function	Protein Binding Fatty Acid Elongase Activity Transferase Activity	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Chondroitin Sulfate Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Immune System Process Inflammatory Response Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell Migration Regulation Of Mast Cell Degranulation Granulocyte Chemotaxis
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (MOSTest) ( 32665545) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Multiple system atrophy ( 27629089) Parkinson's disease ( 32201043 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (MOSTest) ( 32665545) Working memory ( 31598132)	Blood protein levels ( 30072576) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243)
Interacting Genes		12 interacting genes: ADGRE2 DTNBP1 EMP3 LRCH4 RTP2 SERF1A SERF1B SLC41A1 SYNJ2BP TMEM14C UBE2J2 VAMP1	26 interacting genes: AQP6 BIK CCDC107 CD79A CREB3L1 ELOVL4 ELOVL7 ERGIC3 FAM209A FAM210B FCER1G FKBP7 GPR42 HSD17B13 KIR2DL3 LMNA MARCHF6 MMGT1 MTERF3 MTIF3 SAR1A SLC18A1 SLC61A1 SLC7A14 TLCD4 TMEM80
Entrez ID		79993	30817
HPRD ID		18700	07308
Ensembl ID		ENSG00000164181	ENSG00000127507
Uniprot IDs		A1L3X0 D6RHD0	A0JNV7 B4DWB8 Q9UHX3
PDB IDs		6Y7F	2BO2 2BOU 2BOX
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Membrane Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Endoplasmic Reticulum Membrane Serotonin Transport Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Fatty-acyl-CoA Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?