ADGRE2 and SLC7A14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ADGRE2	SLC7A14
Description		adhesion G protein-coupled receptor E2	solute carrier family 7 member 14
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Leading Edge Membrane Ruffle Membrane Cell Projection	Nucleoplasm Lysosome Lysosomal Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Chondroitin Sulfate Binding	Protein Binding Amino Acid Transmembrane Transporter Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Immune System Process Inflammatory Response Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell Migration Regulation Of Mast Cell Degranulation Granulocyte Chemotaxis	Amino Acid Transmembrane Transport Amino Acid Transport Gamma-aminobutyric Acid Import Transmembrane Transport
Pathways		Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243)	Obesity (extreme) ( 30677029) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		26 interacting genes: AQP6 BIK CCDC107 CD79A CREB3L1 ELOVL4 ELOVL7 ERGIC3 FAM209A FAM210B FCER1G FKBP7 GPR42 HSD17B13 KIR2DL3 LMNA MARCHF6 MMGT1 MTERF3 MTIF3 SAR1A SLC18A1 SLC61A1 SLC7A14 TLCD4 TMEM80	47 interacting genes: ACSL5 ADGRE2 AGTRAP AIG1 APOL3 BET1 BNIP1 BNIP2 C1GALT1 CBLIF CCDC167 CCL4L2 CD53 CMTM5 DCBLD2 DERL1 EOGT ERMP1 FAM209A FAM20B FATE1 FCER1G FKBP7 IL10RA LINC00839 LTC4S MFF MGLL MMGT1 NINJ2 NSG1 PLPP6 PRB1 SCARF1 SCD SMCO4 TECR TMEM128 TMEM31 TRARG1 TREX1 UBIAD1 VAMP2 VKORC1 YIPF4 YIPF6 ZFPL1
Entrez ID		30817	57709
HPRD ID		07308	17222
Ensembl ID		ENSG00000127507	ENSG00000013293
Uniprot IDs		A0JNV7 B4DWB8 Q9UHX3	Q8TBB6
PDB IDs		2BO2 2BOU 2BOX
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Endoplasmic Reticulum Membrane Serotonin Transport Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Fatty-acyl-CoA Biosynthetic Process	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organelle Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Fusion SNAP Receptor Activity Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Vesicle Fusion Vesicle Fusion With Golgi Apparatus Cobalt Ion Transport SNARE Complex Nuclear Envelope Fatty Acid Biosynthetic Process Intestinal Epithelial Cell Development Response To Oxygen-glucose Deprivation Establishment Of Protein Localization To Plasma Membrane Vitamin K Metabolic Process Endosome To Plasma Membrane Protein Transport Endomembrane System Columnar/cuboidal Epithelial Cell Development Golgi Vesicle Transport
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