ELOVL7 and LRCH4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ELOVL7	LRCH4
Description		ELOVL fatty acid elongase 7	leucine rich repeats and calponin homology domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane PML Body
	Molecular Function	Protein Binding Fatty Acid Elongase Activity Transferase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Membrane Raft Assembly Nervous System Development Positive Regulation Of Toll-like Receptor Signaling Pathway
Pathways		Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (MOSTest) ( 32665545) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Multiple system atrophy ( 27629089) Parkinson's disease ( 32201043 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (MOSTest) ( 32665545) Working memory ( 31598132)	Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: ADGRE2 DTNBP1 EMP3 LRCH4 RTP2 SERF1A SERF1B SLC41A1 SYNJ2BP TMEM14C UBE2J2 VAMP1	16 interacting genes: CA8 CYB5R3 ELOVL7 HSD17B11 KASH5 KRT40 KRTAP10-7 KRTAP10-8 MDFI NOTCH2NLA RBBP6 RETREG3 RNASEK RTN4 SIN3A SPOP
Entrez ID		79993	4034
HPRD ID		18700	10062
Ensembl ID		ENSG00000164181	ENSG00000077454
Uniprot IDs		A1L3X0 D6RHD0	B4DYF8 H7C5D9 O75427
PDB IDs		6Y7F
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Keratin Filament
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