TEFM and SPCS2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		TEFM	SPCS2
Description		transcription elongation factor, mitochondrial	signal peptidase complex subunit 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Ribonucleoprotein Complex	Endoplasmic Reticulum Signal Peptidase Complex Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Nucleic Acid Binding Transcription Elongation Factor Activity RNA Binding Protein Binding Crossover Junction DNA Endonuclease Activity	Protein Binding
	Biological Process	Regulation Of Oxidative Phosphorylation Mitochondrial DNA Replication Transcription Elongation By Mitochondrial RNA Polymerase Positive Regulation Of Mitochondrial Transcription	Signal Peptide Processing Protein Targeting To ER
Pathways			SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin Regulation of CDH1 posttranslational processing and trafficking to plasma membrane Maturation of hRSV A proteins
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Height ( 28552196)
Interacting Genes		2 interacting genes: PPP1CC SPCS2	6 interacting genes: ATP13A2 CLN8 EGFR FNDC3B STMN3 TEFM
Entrez ID		79736	9789
HPRD ID		08005	15435
Ensembl ID		ENSG00000172171	ENSG00000118363
Uniprot IDs		Q96QE5	Q15005
PDB IDs		5OL8 5OL9 5OLA 8U8U 8U8V 9BDC 9BDD	7P2P 7P2Q
Enriched GO Terms of Interacting Partners?		Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock By Photoperiod Blastocyst Development Positive Regulation Of Glial Cell Proliferation PTW/PP1 Phosphatase Complex Entrainment Of Circadian Clock Lamin Binding Protein Targeting To ER Signal Peptide Processing Signal Peptidase Complex Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Glial Cell Proliferation Mitotic Sister Chromatid Segregation Sister Chromatid Segregation	Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Negative Regulation Of Protein Catabolic Process Shc-EGFR Complex Multivesicular Body, Internal Vesicle Lumen Negative Regulation Of Protein Metabolic Process Somatic Motor Neuron Differentiation Glutamate Reuptake Retinal Rod Cell Apoptotic Process Polyamine Transmembrane Transporter Activity Spermine Transport Extracellular Exosome Biogenesis P-type Transmembrane Transporter Activity Spermine Transmembrane Transport ABC-type Polyamine Transporter Activity Transcription Elongation By Mitochondrial RNA Polymerase Positive Regulation Of Mitochondrial Transcription Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Binding Vacuole Organization Lipid Homeostasis Extracellular Vesicle Biogenesis P-type Ion Transporter Activity Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Autophagosome Size Cupric Ion Binding Negative Regulation Of Rac Protein Signal Transduction Retinal Cell Apoptotic Process Polyamine Transmembrane Transport ERBB2-EGFR Signaling Pathway Ceramide Binding Regulation Of Cellular Component Size Regulation Of Neuron Apoptotic Process Regulation Of Chaperone-mediated Autophagy Cellular Response To Manganese Ion Transcription Elongation Factor Activity Crossover Junction DNA Endonuclease Activity Learning Or Memory Salivary Gland Morphogenesis Neurofilament Cytoskeleton Organization L-glutamate Import Across Plasma Membrane ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Regulation Of Lysosomal Protein Catabolic Process Mitochondrial DNA Replication Regulation Of Mitochondrial Transcription
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