SPCS2

Gene Name		signal peptidase complex subunit 2 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Peptidase Activity
	Biological Process	Translation Signal Peptide Processing Proteolysis SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Cellular Protein Metabolic Process Regulation Of Insulin Secretion
Pathways		Peptide hormone metabolism Synthesis, secretion, and deacylation of Ghrelin Translation Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Incretin synthesis, secretion, and inactivation
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: ATP13A2 CLN8 EGFR STMN3 TEFM
Entrez ID		9789
HPRD ID		15435
Ensembl ID		ENSG00000118363
Uniprot IDs		Q15005
PDB IDs
Enriched GO Terms of Interacting Partners?		Alkanesulfonate Metabolic Process Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation L-glutamate Uptake Involved In Synaptic Transmission Regulation Of Catalytic Activity Activation Of Phospholipase A2 Activity Cellular Response To Manganese Ion Positive Regulation Of Phospholipase A2 Activity Neuron Differentiation Age-dependent Response To Oxidative Stress Response To Cobalamin Response To UV-A Learning Or Memory Negative Regulation Of Rac Protein Signal Transduction Response To Hydroxyisoflavone Cognition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Somatic Motor Neuron Differentiation L-glutamate Import Response To Metal Ion Microtubule Depolymerization Positive Regulation Of Catenin Import Into Nucleus Transcription From Mitochondrial Promoter Regulation Of Phospholipase A2 Activity Generation Of Neurons Regulation Of Superoxide Anion Generation Neurotransmitter Uptake Mitochondrion Organization Neurofilament Cytoskeleton Organization Response To Oxidative Stress Neurogenesis Magnesium Ion Homeostasis Neuromuscular Process Controlling Posture Single-organism Behavior Amino Acid Import Response To Inorganic Substance Response To Manganese Ion Cellular Response To Estradiol Stimulus Protein Insertion Into Membrane Astrocyte Development Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Catenin Import Into Nucleus Regulation Of Rac GTPase Activity Cellular Response To Epidermal Growth Factor Stimulus Response To Epidermal Growth Factor Sensory Organ Development L-glutamate Transport Behavior
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