AAGAB and AP1S3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AAGAB	AP1S3
Gene Name		alpha- and gamma-adaptin binding protein	adaptor-related protein complex 1, sigma 3 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Golgi Membrane Lysosomal Membrane Cytosol Coated Pit Membrane Coat Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane
	Molecular Function		Protein Transporter Activity
	Biological Process	Protein Transport	Protein Targeting Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways			Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: AP1S3 AP2S1 EIF3C HEATR1 UNC119	2 interactors: AAGAB PRKAG1
Entrez ID		79719	130340
HPRD ID		07754	16495
Ensembl ID		ENSG00000103591	ENSG00000152056
Uniprot IDs		B4DG44 Q6PD74	Q96PC3
PDB IDs			4HMY
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis Cytokinesis, Completion Of Separation Regulation Of Endocytosis Antigen Processing And Presentation Of Peptide Antigen Regulation Of Caveolin-mediated Endocytosis Antigen Processing And Presentation Mitotic Cytokinetic Process Ribonucleoprotein Complex Biogenesis Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Vesicle-mediated Transport Regulation Of Clathrin-mediated Endocytosis Cell Separation After Cytokinesis Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Transport Regulation Of Transcription From RNA Polymerase I Promoter Formation Of Translation Preinitiation Complex Protein Localization Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Viral Process Synaptic Transmission Maturation Of SSU-rRNA Cellular Macromolecular Complex Assembly Endocytosis Clathrin Coat Assembly Positive Regulation Of Protein Tyrosine Kinase Activity Clathrin-mediated Endocytosis Ribosomal Small Subunit Biogenesis Mitotic Cytokinesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Endocytosis Negative Regulation Of ERBB Signaling Pathway Membrane Organization Regulation Of Protein Tyrosine Kinase Activity Intracellular Protein Transport Cell-cell Signaling
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