MORC4 and GEMIN4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MORC4	GEMIN4
Gene Name		MORC family CW-type zinc finger 4	gem (nuclear organelle) associated protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Vesicular Exosome Gemini Of Coiled Bodies
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process		Spliceosomal SnRNP Assembly RRNA Processing Gene Expression NcRNA Metabolic Process
Pathways			snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS		Pancreatitis ( 23143602)	Prostate cancer ( 23535732)
Protein-Protein Interactions		4 interactors: GEMIN4 PRKAA1 SKIL STAT3	25 interactors: AGO2 CALCOCO2 DDX20 DHX9 DMPK FLAD1 GEMIN5 GLYR1 KARS LGALS1 LGALS3 MORC4 PIAS3 RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD1 SNRPD2 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TOP1
Entrez ID		79710	50628
HPRD ID		06757	07370
Ensembl ID		ENSG00000133131	ENSG00000179409
Uniprot IDs		B4DTP6 Q8TE76	I3L2C7 P57678 Q8WUM5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Glycolytic Process Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Protein Heterooligomerization Response To Ethanol Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Arrest Regulation Of Carbohydrate Metabolic Process RNA Metabolic Process Glucose Homeostasis Gene Expression Negative Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Signal Transduction Response To Camptothecin Negative Regulation Of Biosynthetic Process Homeostatic Process Negative Regulation Of Sphingolipid Biosynthetic Process Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Cell Death Cellular Response To Peptide Regulation Of Ceramide Biosynthetic Process Negative Regulation Of Glycolytic Process Positive Regulation Of Cholesterol Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cholesterol Metabolic Process Radial Glial Cell Differentiation Cellular Response To Ethanol Eye Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Glucose Import Cellular Response To Organic Substance Protein Heterotrimerization Regulation Of Energy Homeostasis Protein Oligomerization Cellular Component Assembly Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Glycolytic Process Negative Regulation Of Cell Cycle Response To Peptide Hormone Cellular Response To Organonitrogen Compound Interleukin-6-mediated Signaling Pathway Fatty Acid Homeostasis Response To Peptide Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Nitrogen Compound Metabolic Process Protein Homotrimerization	Spliceosomal SnRNP Assembly RNA Processing MRNA Processing NcRNA Metabolic Process Ribonucleoprotein Complex Assembly MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Biogenesis Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Neutrophil Degranulation RNA Metabolic Process Nitrogen Compound Metabolic Process Neutrophil Activation Involved In Immune Response Gene Expression Immune Response Cellular Component Assembly Neutrophil Mediated Immunity Production Of MiRNAs Involved In Gene Silencing By MiRNA Neutrophil Activation Immune System Process Leukocyte Activation Involved In Immune Response Gene Silencing By MiRNA Cellular Response To DsRNA Posttranscriptional Gene Silencing Leukocyte Degranulation Lysyl-tRNA Aminoacylation Negative Regulation Of Immunological Synapse Formation FAD Biosynthetic Process Positive Regulation Of Erythrocyte Aggregation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Spliceosomal Complex Assembly Gene Silencing By RNA Cellular Metabolic Process MRNA Cleavage Involved In Gene Silencing By MiRNA Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Diadenosine Tetraphosphate Biosynthetic Process Response To DsRNA Cellular Process Vesicle Docking Membrane Docking SiRNA Loading Onto RISC Involved In RNA Interference Positive Regulation Of Mononuclear Cell Migration Mononuclear Cell Migration
Tagcloud ?			a1 a11 a2 a4 a5 a6 accomplishments annealing annexin annexins carbohydrate conjunction cytoplasm cytoskeleton extensively galectin galectins helicase inside interacting lectin lectins outside phospholipid possesses primer summarizes synexin unwinding
Tagcloud (Difference) ?			a1 a11 a2 a4 a5 a6 accomplishments annealing annexin annexins carbohydrate conjunction cytoplasm cytoskeleton extensively galectin galectins helicase inside interacting lectin lectins outside phospholipid possesses primer summarizes synexin unwinding
Tagcloud (Intersection) ?