VCPKMT and ASPSCR1

Number of citations of the paper that reports this interaction (PubMedID 23349634)
81

Data Source:
BioGRID (pull down)

		VCPKMT	ASPSCR1
Description		valosin containing protein lysine methyltransferase	ASPSCR1 tether for SLC2A4, UBX domain containing
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GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Methyltransferase Activity Protein Methyltransferase Activity Protein-lysine N-methyltransferase Activity Transferase Activity ATPase Binding	Protein Binding
	Biological Process	Peptidyl-lysine Methylation Peptidyl-lysine Trimethylation Methylation Negative Regulation Of ATP-dependent Activity	Intracellular Protein Transport Positive Regulation Of Protein Modification Process Glucose Homeostasis Regulation Of D-glucose Import
Pathways		Protein methylation	Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases			Alveolar soft part sarcoma
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874)	Appendicular lean mass ( 33097823) Birth weight ( 31043758) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Lung function (FVC) ( 30804560) Offspring birth weight ( 31043758) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: ASPSCR1 CARD9 VCP	17 interacting genes: ADAMTSL4 APP CLK2 INCA1 KRT31 KRTAP1-1 KRTAP10-8 NEDD4 NOTCH2NLA NSF PHAX TACC3 TCF4 UBC VCP VCPKMT WEE2-AS1
Entrez ID		79609	79058
HPRD ID		16605	06947
Ensembl ID		ENSG00000100483	ENSG00000169696
Uniprot IDs		Q9H867	Q9BZE9
PDB IDs		4LG1 7OAT 8HL6 8HL7	5IFS 5IFW 7OAT
Enriched GO Terms of Interacting Partners?		Flavin Adenine Dinucleotide Catabolic Process VCP-NSFL1C Complex Cellular Response To Arsenite Ion Positive Regulation Of Protein Metabolic Process Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Mitotic Spindle Disassembly Positive Regulation Of Oxidative Phosphorylation Positive Regulation Of Protein K63-linked Deubiquitination Cytoplasm Protein Quality Control Regulation Of Protein Metabolic Process BAT3 Complex Binding Positive Regulation Of Protein Deubiquitination CBM Complex Protein-DNA Covalent Cross-linking Repair Stress Granule Disassembly Positive Regulation Of Mitochondrial Membrane Potential Inclusion Body Assembly Aggresome Assembly Negative Regulation Of Protein Localization To Chromatin Derlin-1 Retrotranslocation Complex Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway VCP-NPL4-UFD1 AAA ATPase Complex Positive Regulation Of Protein Modification Process Regulation Of Protein Localization To Chromatin Deubiquitinase Activator Activity Host-mediated Modulation Of Intestinal Microbiota Composition Regulation Of Protein Deubiquitination Positive Regulation Of Membrane Potential K48-linked Polyubiquitin Modification-dependent Protein Binding ATPase Complex Ubiquitin-modified Protein Reader Activity Cellular Response To Misfolded Protein Positive Regulation Of Cellular Respiration Response To Misfolded Protein Positive Regulation Of ATP Biosynthetic Process Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Antifungal Innate Immune Response Response To Peptidoglycan CARD Domain Binding Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Retrograde Protein Transport, ER To Cytosol Intracellular Protein Transport Cellular Response To Arsenic-containing Substance Response To Aldosterone MHC Class I Protein Binding Regulation Of ATP Biosynthetic Process Ubiquitin-specific Protease Binding Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of T-helper 17 Type Immune Response Viral Genome Replication
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