OBI1 and CNOT11

Number of citations: 102 (PubMedID 34887419)
Data Source: BioGRID (pull down)

		OBI1	CNOT11
Name		ORC ubiquitin ligase 1	CCR4-NOT transcription complex subunit 11
Structure		No pdb structure
GO Annotations	Cellular Component	Chromatin Chromosome	Nucleus Cytoplasm Cytosol CCR4-NOT Complex
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Regulation Of DNA Replication Protein Monoubiquitination Protein Autoubiquitination	Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Translation Regulatory NcRNA-mediated Gene Silencing
Pathways		Cyclin A/B1/B2 associated events during G2/M transition	Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain M-decay: degradation of maternal mRNAs by maternally stored factors
GWAS		No GWAS studies recorded	Carotid intima media thickness x smoking interaction ( 32117412 )
Interacting Genes		13 interacting genes: CNOT1 CNOT10 CNOT11 CNOT2 CNOT3 CNOT6 CNOT7 CNOT9 PNKP SRPK2 TCEANC UBE2D1 UBE2D2	5 interacting genes: CATSPERT FAM193B MEOX1 OBI1 OGT
Entrez ID		79596	55571
HPRD ID		12619	12812
Ensembl ID		ENSG00000152193	ENSG00000158435
Uniprot IDs		Q5W0B1	Q9UKZ1
PDB IDs		Not available	8BFH 8BFI 8BFJ 8FY3
GO Terms Enriched among Interactors		CCR4-NOT Complex Nuclear-transcribed MRNA Poly(A) Tail Shortening CCR4-NOT Core Complex Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Regulatory NcRNA-mediated Gene Silencing RNA Catabolic Process Nucleobase-containing Compound Catabolic Process MRNA Metabolic Process Poly(A)-specific Ribonuclease Activity Regulation Of Translation Macromolecule Catabolic Process Post-transcriptional Regulation Of Gene Expression RNA Metabolic Process Nucleic Acid Metabolic Process P-body Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Nucleobase-containing Compound Metabolic Process Catabolic Process Macromolecule Metabolic Process Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Protein Metabolic Process Trophectodermal Cell Differentiation Negative Regulation Of Gene Expression Nucleus Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Primary Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Organelle Assembly MRNA Destabilization RNA Exonuclease Activity RNA Destabilization Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of MRNA Catabolic Process Regulation Of MRNA Metabolic Process Regulatory NcRNA-mediated Post-transcriptional Gene Silencing	None