OBI1

Name	ORC ubiquitin ligase 1
Structure	No pdb structure
Interactors	13 interactors: CNOT1 CNOT10 CNOT11 CNOT2 CNOT3 CNOT6 CNOT7 CNOT9 PNKP SRPK2 TCEANC UBE2D1 UBE2D2
GO Annotations	Cellular Component	Chromatin Chromosome
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of DNA Replication Protein Monoubiquitination Protein Autoubiquitination
Pathways	Cyclin A/B1/B2 associated events during G2/M transition
GWAS	No GWAS studies recorded
Entrez ID	79596
HPRD ID	12619
Ensembl ID	ENSG00000152193
Uniprot IDs	Q5W0B1
PDB IDs	Not available
GO Terms Enriched among Interactors ?	CCR4-NOT Complex Nuclear-transcribed MRNA Poly(A) Tail Shortening CCR4-NOT Core Complex Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Regulatory NcRNA-mediated Gene Silencing RNA Catabolic Process Nucleobase-containing Compound Catabolic Process MRNA Metabolic Process Poly(A)-specific Ribonuclease Activity Regulation Of Translation Macromolecule Catabolic Process Post-transcriptional Regulation Of Gene Expression RNA Metabolic Process Nucleic Acid Metabolic Process P-body Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Nucleobase-containing Compound Metabolic Process Catabolic Process Macromolecule Metabolic Process Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Protein Metabolic Process Trophectodermal Cell Differentiation Negative Regulation Of Gene Expression Nucleus Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Primary Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Organelle Assembly MRNA Destabilization RNA Exonuclease Activity RNA Destabilization Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of MRNA Catabolic Process Regulation Of MRNA Metabolic Process Regulatory NcRNA-mediated Post-transcriptional Gene Silencing