SAP130 and CSN1S1

Number of citations of the paper that reports this interaction (PMID 18173839)
8

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SAP130	CSN1S1
Gene Name		Sin3A-associated protein, 130kDa	casein alpha s1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm STAGA Complex	Extracellular Region Extracellular Space
	Molecular Function	Transcription Coactivator Activity Histone Acetyltransferase Activity	Transporter Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Gene Expression Regulation Of Gene Expression, Epigenetic Histone H3 Acetylation Negative Regulation Of Gene Expression, Epigenetic	Transport
Pathways		NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ARID4B CSN1S1 CUL2 MYC SMAD3	11 interactors: CSNK2A1 CSNK2B HTRA2 PARK7 PLK1 PPM1J PRSS2 SAP130 STK4 TOLLIP TTBK1
Entrez ID		79595	1446
HPRD ID		18015	00280
Ensembl ID		ENSG00000136715	ENSG00000126545
Uniprot IDs		Q9H0E3	P47710
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Arrest Negative Regulation Of Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Cell Proliferation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Positive Regulation Of Cysteine-type Endopeptidase Activity Mesonephros Development Positive Regulation Of Endopeptidase Activity Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Peptidase Activity Fibroblast Apoptotic Process Kidney Epithelium Development Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cell Cycle Evasion Or Tolerance Of Host Defenses By Virus Response To Transforming Growth Factor Beta Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Programmed Cell Death Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression, Epigenetic Cell Cycle Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Cell Death Death Epithelium Development DNA-templated Transcription, Initiation Response To Abiotic Stimulus Regulation Of Extracellular Matrix Assembly Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Establishment Of Sertoli Cell Barrier Primary MiRNA Processing Negative Regulation Of Monocyte Differentiation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Cell Proliferation Involved In Kidney Development Regulation Of Epithelial Cell Proliferation Positive Regulation Of Proteolysis Response To Hypoxia SMAD Protein Complex Assembly Negative Regulation Of Osteoblast Proliferation Histone H4-K20 Trimethylation Negative Regulation Of Gene Expression	Positive Regulation Of Protein Metabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Protein Metabolic Process Regulation Of Binding Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Peptidyl-serine Phosphorylation Positive Regulation Of Protein Modification Process Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Binding Regulation Of Protein Sumoylation Peptidyl-amino Acid Modification Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Response To Toxic Substance Negative Regulation Of Oxidative Stress-induced Cell Death Phosphorylation Phosphate-containing Compound Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Growth Positive Regulation Of Signal Transduction Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Proteolysis Protein Phosphorylation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Response To Oxidative Stress Positive Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Apoptotic Process Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Cell Death Positive Regulation Of Protein Binding Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		clearance closure comprehensively dedifferentiate drastic edge enable fluorescently healing kismet mip120 modifying motile osa partly periphery practical publicly pvr reporter reporters repressed sin3a spt6 tagged tagging thirteen underlie wound	0x 1x 25x 2x 4ebp1 4x 5x 8x arg arginine bovine casein conditionally csn2 csn3 devoid except excess experimental gland mammary mtor output resemble s6k stat5 true
Tagcloud (Difference) ?		clearance closure comprehensively dedifferentiate drastic edge enable fluorescently healing kismet mip120 modifying motile osa partly periphery practical publicly pvr reporter reporters repressed sin3a spt6 tagged tagging thirteen underlie wound	0x 1x 25x 2x 4ebp1 4x 5x 8x arg arginine bovine casein conditionally csn2 csn3 devoid except excess experimental gland mammary mtor output resemble s6k stat5 true
Tagcloud (Intersection) ?