TFEB and TFEC

Number of citations of the paper that reports this interaction (PMID 9806910)
25

Data Source:
HPRD (in vivo)

		TFEB	TFEC
Gene Name		transcription factor EB	transcription factor EC
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding Protein Dimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Dimerization Activity
	Biological Process	Embryonic Placenta Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Autophagy Humoral Immune Response Lysosome Organization Positive Regulation Of Autophagy Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To Heat Negative Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		4 interactors: MITF SRPK1 TFE3 TFEC	8 interactors: DCK DEFB127 HNRNPA1 MITF NAPB TFE3 TFEB ZMAT2
Entrez ID		7942	22797
HPRD ID		02847	05294
Ensembl ID		ENSG00000112561	ENSG00000105967
Uniprot IDs		B0QYS6 P19484	O14948
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Osteoclast Differentiation Regulation Of Myeloid Leukocyte Differentiation Regulation Of Myeloid Cell Differentiation RNA Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Sperm Chromatin Condensation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Immune System Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Positive Regulation Of Viral Genome Replication RNA Biosynthetic Process Spermatid Nucleus Differentiation Melanocyte Differentiation Osteoclast Differentiation Negative Regulation Of Viral Genome Replication Neuroepithelial Cell Differentiation Bone Remodeling Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Heat Developmental Pigmentation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Viral Process Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Response To Stimulus Regulation Of MRNA Processing Canonical Wnt Signaling Pathway Immune Response Regulation Of Immune System Process Regulation Of RNA Splicing Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Response To Heat Tissue Remodeling Myeloid Leukocyte Differentiation Pigmentation Nucleus Organization	Regulation Of Osteoclast Differentiation Regulation Of Myeloid Leukocyte Differentiation Regulation Of Myeloid Cell Differentiation SNARE Complex Disassembly Humoral Immune Response Immune System Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Immune Response Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Purine-containing Compound Salvage Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process
Tagcloud ?		adaptors alters axonally delays endosomal enlarged enlarges fatal fronto ftld highlighting illumination lamp lobar lumenal lysosomal lysosomes organelle photodamage reporters soma sted tdp tmem106 tmem106b torin traffic transported yields	advantage agonists augment autonomous believed competitive confer conservation define determinants engineered enhance fos hsc hscs intrinsically klf10 majority namely niches osteoclastogenesis prdm16 renewal robust screen spi1 supports surprisingly unexpectedly
Tagcloud (Difference) ?		adaptors alters axonally delays endosomal enlarged enlarges fatal fronto ftld highlighting illumination lamp lobar lumenal lysosomal lysosomes organelle photodamage reporters soma sted tdp tmem106 tmem106b torin traffic transported yields	advantage agonists augment autonomous believed competitive confer conservation define determinants engineered enhance fos hsc hscs intrinsically klf10 majority namely niches osteoclastogenesis prdm16 renewal robust screen spi1 supports surprisingly unexpectedly
Tagcloud (Intersection) ?