ABAT and ALDH5A1

Number of citations of the paper that reports this interaction (PMID 6470007)
3

Data Source:
HPRD (in vitro)

		ABAT	ALDH5A1
Gene Name		4-aminobutyrate aminotransferase	aldehyde dehydrogenase 5 family, member A1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix 4-aminobutyrate Transaminase Complex Neuron Projection Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Matrix
	Molecular Function	4-aminobutyrate Transaminase Activity Pyridoxal Phosphate Binding Succinate-semialdehyde Dehydrogenase Binding Protein Homodimerization Activity (S)-3-amino-2-methylpropionate Transaminase Activity	Aldehyde Dehydrogenase (NAD) Activity Succinate-semialdehyde Dehydrogenase (NAD+) Activity Succinate-semialdehyde Dehydrogenase [NAD(P)+] Activity Protein Homodimerization Activity
	Biological Process	Response To Hypoxia Synaptic Transmission Neurotransmitter Secretion Copulation Locomotory Behavior Gamma-aminobutyric Acid Catabolic Process Response To Iron Ion Response To Nicotine Neurotransmitter Catabolic Process Response To Drug Response To Ethanol Negative Regulation Of Blood Pressure Behavioral Response To Cocaine	Glucose Metabolic Process Acetate Metabolic Process Succinate Metabolic Process Glutamate Metabolic Process Glutamine Metabolic Process Glycerophospholipid Metabolic Process Glucosylceramide Metabolic Process Galactosylceramide Metabolic Process Glutathione Metabolic Process Synaptic Transmission Neurotransmitter Secretion Central Nervous System Development Gamma-aminobutyric Acid Catabolic Process Post-embryonic Development Respiratory Electron Transport Chain Neurotransmitter Catabolic Process Short-chain Fatty Acid Metabolic Process Protein Homotetramerization
Pathways		Neurotransmitter Release Cycle Degradation of GABA GABA synthesis, release, reuptake and degradation Transmission across Chemical Synapses	Neurotransmitter Release Cycle Degradation of GABA GABA synthesis, release, reuptake and degradation Transmission across Chemical Synapses
Drugs		Pyridoxal Phosphate Pyruvic acid L-Glutamic Acid L-Alanine Valproic Acid Phenelzine Vigabatrin (4e)-4-Aminohex-4-Enoic Acid 4-Amino Hexanoic Acid	Succinic acid NADH Valproic Acid Chlormerodrin
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-Protein Interactions		1 interactors: ALDH5A1	2 interactors: ABAT MAGEA11
Entrez ID		18	7915
HPRD ID		00661	08361
Ensembl ID		ENSG00000183044	ENSG00000112294
Uniprot IDs		P80404	P51649 Q546H9
PDB IDs			2W8N 2W8O 2W8P 2W8Q 2W8R
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyric Acid Catabolic Process Acetate Metabolic Process Glucosylceramide Metabolic Process Succinate Metabolic Process Neurotransmitter Catabolic Process Gamma-aminobutyric Acid Metabolic Process Short-chain Fatty Acid Metabolic Process Galactosylceramide Metabolic Process Glutamate Metabolic Process Glycosylceramide Metabolic Process Neurotransmitter Metabolic Process Glutamine Metabolic Process Protein Homotetramerization Glutathione Metabolic Process Glycosphingolipid Metabolic Process Ceramide Metabolic Process Dicarboxylic Acid Metabolic Process Protein Tetramerization Neurotransmitter Secretion Respiratory Electron Transport Chain Cellular Amino Acid Catabolic Process Electron Transport Chain Glycolipid Metabolic Process Regulation Of Neurotransmitter Levels Post-embryonic Development Glucose Metabolic Process Peptide Metabolic Process Sphingolipid Metabolic Process Neurotransmitter Transport Cellular Respiration Carboxylic Acid Catabolic Process Hexose Metabolic Process Membrane Lipid Metabolic Process Cellular Modified Amino Acid Metabolic Process Monosaccharide Metabolic Process Cellular Amide Metabolic Process Protein Homooligomerization Alpha-amino Acid Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Glycerophospholipid Metabolic Process Fatty Acid Metabolic Process Sulfur Compound Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Generation Of Precursor Metabolites And Energy Protein Oligomerization Cellular Amino Acid Metabolic Process Secretion By Cell Monocarboxylic Acid Metabolic Process Synaptic Transmission	Gamma-aminobutyric Acid Catabolic Process Gamma-aminobutyric Acid Metabolic Process Behavioral Response To Cocaine Neurotransmitter Catabolic Process Copulation Neurotransmitter Metabolic Process Response To Iron Ion Response To Nicotine Negative Regulation Of Blood Pressure Response To Cocaine Mating Response To Ammonium Ion Neurotransmitter Secretion Cellular Amino Acid Catabolic Process Regulation Of Neurotransmitter Levels Response To Ethanol Response To Alkaloid Adult Behavior Neurotransmitter Transport Regulation Of Blood Pressure Carboxylic Acid Catabolic Process Locomotory Behavior Response To Hypoxia Blood Circulation Response To Metal Ion Single-organism Behavior Cellular Amino Acid Metabolic Process Response To Inorganic Substance Secretion By Cell Response To Drug Monocarboxylic Acid Metabolic Process Synaptic Transmission Behavior Secretion
Tagcloud ?		16p13 2p13 3p13 anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 rbfox1 spanning tmem114 vertebral
Tagcloud (Difference) ?		16p13 2p13 3p13 anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 rbfox1 spanning tmem114 vertebral
Tagcloud (Intersection) ?