ZNF426 and USP25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF426	USP25
Gene Name		zinc finger protein 426	ubiquitin specific peptidase 25
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	DNA Binding Metal Ion Binding	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity SUMO Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Cellular Protein Modification Process Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Panic disorder ( 19165232) Parkinson's disease ( 21738487)
Protein-Protein Interactions		15 interactors: CALCOCO2 CCDC85B CEP70 CIB3 EFEMP2 GLRX3 KRTAP4-12 LPXN LZTS2 MDFI MPPE1 MTUS2 NINL TSGA10 USP25	14 interactors: ACTA1 FLNC GAPDH MAGEB4 MT2A RAD23A SENP1 SKIL SUMO1 SUMO2 SYK UBC UBE2I ZNF426
Entrez ID		79088	29761
HPRD ID		15787	05296
Ensembl ID		ENSG00000130818	ENSG00000155313
Uniprot IDs		K7ER43 Q9BUY5	Q9UHP3
PDB IDs
Enriched GO Terms of Interacting Partners?			Protein Sumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Post-translational Protein Modification Peptidyl-amino Acid Modification Peptidyl-lysine Modification Protein Modification By Small Protein Conjugation Positive Regulation Of Proteolysis Regulation Of Proteolysis Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Cytokine Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Interferon-gamma Positive Regulation Of Cellular Protein Catabolic Process Response To Interferon-gamma Response To Organic Substance Viral Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cellular Response To Cytokine Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Muscle Fiber Development Immune Response Negative Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Defense Response Negative Regulation Of Biosynthetic Process Immune System Process Peptidyl-cysteine S-trans-nitrosylation Positive Regulation Of SUMO Transferase Activity Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Metabolic Process JNK Cascade Skeletal Muscle Fiber Adaptation Beta Selection Positive Regulation Of Interleukin-3 Biosynthetic Process Cellular Response To Molecule Of Fungal Origin Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Gene Expression Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?			chains cleaved cys178 cysteine deubiquitinated deubiquitinating deubiquitination dub emerged his607 histidine ifn interferon irf3 lost lysine mechanistically polyubiquitin potentiated proteases residue rig screen traf2 traf6 triggered tumornecrosis ubiquitination usps
Tagcloud (Difference) ?			chains cleaved cys178 cysteine deubiquitinated deubiquitinating deubiquitination dub emerged his607 histidine ifn interferon irf3 lost lysine mechanistically polyubiquitin potentiated proteases residue rig screen traf2 traf6 triggered tumornecrosis ubiquitination usps
Tagcloud (Intersection) ?