KCTD15 and ENSA

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		KCTD15	ENSA
Gene Name		potassium channel tetramerization domain containing 15	endosulfine alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleoplasm Cytoplasm
	Molecular Function		Protein Phosphatase Inhibitor Activity Receptor Binding Ion Channel Inhibitor Activity Protein Phosphatase Type 2A Regulator Activity Phosphatase Inhibitor Activity Potassium Channel Inhibitor Activity Protein Phosphatase 2A Binding
	Biological Process	Multicellular Organismal Development Protein Homooligomerization	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transport Mitotic Nuclear Division Response To Nutrient Response To Glucose Negative Regulation Of Catalytic Activity Regulation Of Catalytic Activity Regulation Of Insulin Secretion Cell Division
Pathways			MASTL Facilitates Mitotic Progression Mitotic Prophase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Body mass index ( 19079260 19079261 20935630) Major depressive disorder ( 23377640) Obesity-related traits ( 23251661) Weight ( 19079260)	Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		7 interactors: ATXN1 ENSA KCTD1 NOTCH2NL REN TRIM27 WIPI1	9 interactors: ABCC8 ACD ARIH2 ENO2 KCTD15 POT1 PSEN1 RAP2A SNCA
Entrez ID		79047	2029
HPRD ID		13765	11927
Ensembl ID		ENSG00000153885	ENSG00000143420
Uniprot IDs		Q96SI1	A6NMQ3 O43768
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Oligomerization Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Negative Regulation Of Interleukin-2 Secretion Vesicle Targeting, Trans-Golgi To Endosome Renin-angiotensin Regulation Of Aldosterone Production Cellular Component Assembly Endosomal Transport Negative Regulation Of Calcium Ion Import Drinking Behavior Response To CGMP Protein Homooligomerization Interferon-gamma Secretion Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Protein Localization To Pre-autophagosomal Structure Protein Complex Assembly Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Angiotensin Maturation Negative Regulation Of RNA Biosynthetic Process Regulation Of Angiotensin Metabolic Process Regulation Of Blood Volume By Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Negative Regulation Of Viral Release From Host Cell Cellular Response To Nitrogen Starvation Golgi To Endosome Transport Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Protein Secretion Negative Regulation Of Phosphorylation Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Nucleophagy Negative Regulation Of Viral Transcription Response To Nutrient Levels Beta-amyloid Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Calcium Ion Import Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Response To Immobilization Stress Response To Extracellular Stimulus Intracellular Transport Regulation Of Cellular Process Response To Stimulus Negative Regulation Of Neuroblast Proliferation Mitochondrion Degradation Vesicle Targeting, To, From Or Within Golgi	Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Positive Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Receptor Recycling Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Transferase Activity Regulation Of Receptor Recycling Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Positive Regulation Of DNA Replication Telomere Maintenance Ammonium Transport Cellular Component Assembly Regulation Of Cellular Component Organization Negative Regulation Of Thrombin Receptor Signaling Pathway Cajal-Retzius Cell Differentiation Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Beta-amyloid Formation Generation Of Precursor Metabolites And Energy Negative Regulation Of DNA Metabolic Process Synaptic Vesicle Transport Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Segmentation Negative Regulation Of Biosynthetic Process Regulation Of DNA Replication Negative Regulation Of Dopamine Metabolic Process Telomere Formation Via Telomerase Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Cellular Respiration Synaptic Transmission Regulation Of Neurotransmitter Levels Positive Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Synaptic Vesicle Targeting
Tagcloud ?		adiposity alleles bcdin3d bdnf bmi chinese circumference dgkg etv5 europeans faim2 former fto gnpda2 hong kong lin7c loci lost mc4r modestly mtch2 negr1 obesity sec16b sh2b1 t2d tmem18 waist
Tagcloud (Difference) ?		adiposity alleles bcdin3d bdnf bmi chinese circumference dgkg etv5 europeans faim2 former fto gnpda2 hong kong lin7c loci lost mc4r modestly mtch2 negr1 obesity sec16b sh2b1 t2d tmem18 waist
Tagcloud (Intersection) ?