TSEN34 and TSEN15

Number of citations of the paper that reports this interaction (PMID 15109492)
44

Data Source:
HPRD (two hybrid)

		TSEN34	TSEN15
Gene Name		TSEN34 tRNA splicing endonuclease subunit	TSEN15 tRNA splicing endonuclease subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Nucleolus	Nucleolus
	Molecular Function	TRNA-intron Endonuclease Activity Nucleic Acid Binding Lyase Activity	TRNA-intron Endonuclease Activity
	Biological Process	TRNA-type Intron Splice Site Recognition And Cleavage MRNA Processing RNA Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Height ( 20881960)
Protein-Protein Interactions		2 interactors: HNRNPD TSEN15	4 interactors: EXOSC4 LMO4 NBPF3 TSEN34
Entrez ID		79042	116461
HPRD ID		10038	12292
Ensembl ID		ENSG00000170892	ENSG00000198860
Uniprot IDs		B4DT51 Q9BSV6	B1ALV0 Q8WW01
PDB IDs			2GW6
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing Circadian Regulation Of Translation MRNA Metabolic Process RNA Processing TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Regulation Of MRNA Stability Regulation Of RNA Stability RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Positive Regulation Of Translation	RNA Phosphodiester Bond Hydrolysis TRNA-type Intron Splice Site Recognition And Cleavage Nucleic Acid Phosphodiester Bond Hydrolysis Nuclear MRNA Surveillance RNA Surveillance DNA Deamination Histone MRNA Catabolic Process NcRNA Metabolic Process MRNA Metabolic Process Spinal Cord Association Neuron Differentiation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Maturation Of 5.8S RRNA Regulation Of Cell Fate Specification Ventral Spinal Cord Interneuron Differentiation RNA Metabolic Process Histone MRNA Metabolic Process Dorsal Spinal Cord Development Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Gene Expression Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Regulation Of Cell Fate Commitment Spinal Cord Motor Neuron Differentiation Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Ventricular Septum Development Ventral Spinal Cord Development Nucleobase-containing Compound Metabolic Process Thymus Development Cell Differentiation In Spinal Cord Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Cellular Nitrogen Compound Metabolic Process Cardiac Septum Development DNA Modification Nitrogen Compound Metabolic Process Neural Tube Closure Spinal Cord Development Cardiac Ventricle Development
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