OTUB2 and MAGEA11

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OTUB2	MAGEA11
Gene Name		OTU deubiquitinase, ubiquitin aldehyde binding 2	melanoma antigen family A, 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Ubiquitin-specific Protease Activity	Protein Binding
	Biological Process	Proteolysis Protein Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: APP ARRDC3 CPSF6 FAM168A KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 PJA1 RBCK1 REL RFFL RNF126 SIAH1 TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 UBC UBE2N USP21 USP28	86 interactors: ACMSD ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 C18orf54 CCDC14 CCDC146 CCDC185 CDC20B CDKN2B CEP76 CLUAP1 COX7A2L CSNK2A1 DIEXF DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A GNPDA1 HOXB5 IL11 IL6ST ILF3 JADE3 KIAA0408 LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 OTUB2 PCBD2 PDE4B PHYH PIN4 PNKD PNKP POLR1D PRDX3 PRKRIP1 PSMF1 RADIL RBM23 SH2D4A SNX20 SNX7 STAR TCEA2 TCEANC TCF25 TEX37 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 USP20 VTA1 WDYHV1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2
Entrez ID		78990	4110
HPRD ID		07620	02281
Ensembl ID		ENSG00000089723	ENSG00000185247
Uniprot IDs		Q96DC9	G5E962 P43364
PDB IDs		1TFF 4FJV
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Viral Release From Host Cell Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Viral Release From Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Signal Transduction Negative Regulation Of Viral Entry Into Host Cell Regulation Of Signal Transduction Protein Polyubiquitination Regulation Of Viral Entry Into Host Cell Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Signaling Cellular Protein Modification Process Negative Regulation Of Viral Process Protein K63-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Response To Cytokine Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Immune Response Defense Response Regulation Of Viral Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Cytokine-mediated Signaling Pathway Regulation Of Intracellular Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Locomotion Immune System Process I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Interferon-gamma Signal Transduction Regulation Of Locomotion Response To Interferon-gamma Negative Regulation Of Viral Transcription Protein Metabolic Process Signaling Regulation Of Cellular Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway	Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Gene Expression Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Metabolic Process Protein Polyubiquitination Negative Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Testosterone Biosynthetic Process Regulation Of Cell Death Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Protein Metabolic Process Rhythmic Process Cell Death Response To Lipopolysaccharide Death Negative Regulation Of Protein Metabolic Process Respiratory Electron Transport Chain Response To Molecule Of Bacterial Origin Regulation Of Cell Cycle Electron Transport Chain Oxidation-reduction Process Negative Regulation Of Catalytic Activity RNA Methylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Apoptotic Process Reproductive Structure Development Positive Regulation Of Gene Expression Reproductive System Development Negative Regulation Of Mitotic Cell Cycle Phase Transition Programmed Cell Death
Tagcloud ?		antiviral attenuation coimmunoprecipitations deubiquitinating deubiquitination e3 emerged enzymes ifn ifnb1 induction interacted interferon irf3 knockdown ligases negatively opposite otub1 regulate regulators regulatory traf3 traf6 translational triggered ubiquitin ubiquitination virus
Tagcloud (Difference) ?		antiviral attenuation coimmunoprecipitations deubiquitinating deubiquitination e3 emerged enzymes ifn ifnb1 induction interacted interferon irf3 knockdown ligases negatively opposite otub1 regulate regulators regulatory traf3 traf6 translational triggered ubiquitin ubiquitination virus
Tagcloud (Intersection) ?