NPHS2 and KIRREL3

Number of citations of the paper that reports this interaction (PubMedID 12424224)
0

Data Source:
HPRD (in vivo)

		NPHS2	KIRREL3
Description		NPHS2 stomatin family member, podocin	kirre like nephrin family adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Cell-cell Junction Cytoplasmic Side Of Plasma Membrane Membrane Protein-containing Complex Slit Diaphragm Membrane Raft Extracellular Exosome Cell Periphery	Extracellular Region Plasma Membrane Cell-cell Junction Synaptic Vesicle Membrane Axon Dendrite Dendritic Shaft
	Molecular Function	Protein Binding	Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Glomerular Filtration Gene Expression Actin Cytoskeleton Organization Renal System Development Metanephric Podocyte Development	Neuron Migration Inter-male Aggressive Behavior Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Principal Sensory Nucleus Of Trigeminal Nerve Development Hippocampus Development Hemopoiesis Neuron Projection Morphogenesis Glomerulus Morphogenesis Cell-cell Adhesion
Pathways		Nephrin family interactions	Nephrin family interactions
Drugs
Diseases		Nephrotic syndrome and focal segmental glomerulosclerosis	Non-syndromic autosomal dominant mental retardation
GWAS			Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Body size at age 10 ( 32376654) Breast size ( 22747683) Chronotype ( 30696823) Fasting plasma glucose ( 31170924) Femur bone mineral density x serum urate levels interaction ( 34046847) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Hepcidin/ferritin ratio ( 27846281) Hip circumference ( 28552196) Hippocampal sclerosis ( 25188341) Lamb consumption ( 32066663) Meat-related diet ( 32066663) Menarche (age at onset) ( 23667675) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Positive urgency ( 30718321) Protein quantitative trait loci ( 18464913) Response to antipsychotic treatment ( 20195266) Serum alkaline phosphatase levels ( 33339817 33547301)
Interacting Genes		7 interacting genes: CD2AP FOXC1 FOXC2 KIRREL1 KIRREL3 LMX1B NPHS1	1 interacting genes: NPHS2
Entrez ID		7827	84623
HPRD ID		05303	09679
Ensembl ID		ENSG00000116218	ENSG00000149571
Uniprot IDs		Q9NP85	E9PRX9 Q8IZU9
PDB IDs			2CRY
Enriched GO Terms of Interacting Partners?		Apoptotic Process Involved In Outflow Tract Morphogenesis Negative Regulation Of Apoptotic Process Involved In Outflow Tract Morphogenesis Regulation Of Apoptotic Process Involved In Outflow Tract Morphogenesis Cell-cell Junction Apoptotic Process Involved In Heart Morphogenesis Glomerular Epithelium Development Paraxial Mesoderm Formation Renal Protein Absorption Slit Diaphragm Cell Adhesion Molecule Binding Lymph Vessel Development Endothelium Development Podocyte Differentiation Cell Junction Organization Cell-cell Adhesion Kidney Development Embryonic Heart Tube Development Apoptotic Process Involved In Morphogenesis Cell-cell Junction Organization Myosin Binding Neural Crest Cell Development Cardiac Muscle Cell Proliferation Cell Differentiation Involved In Kidney Development Apoptotic Process Involved In Development Stem Cell Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Epithelium Development Extracellular Matrix Organization Tissue Development Extracellular Structure Organization Ureteric Bud Development Dendritic Shaft Blood Vessel Remodeling Regionalization Renal Absorption Cellular Developmental Process Muscle Cell Proliferation Ventricular Cardiac Muscle Tissue Morphogenesis Mesoderm Formation Somitogenesis Mesonephric Tubule Development Mesonephric Epithelium Development Positive Regulation Of Actin Filament Polymerization Segmentation Cell Adhesion Cell Development Heart Morphogenesis Cardiac Muscle Tissue Morphogenesis Formation Of Primary Germ Layer Regulation Of Actin Cytoskeleton Organization	Metanephric Podocyte Development Renal System Development Slit Diaphragm Podocyte Development Glomerular Filtration Renal Filtration Cell Periphery Renal System Process Cytoplasmic Side Of Plasma Membrane Epithelial Cell Development Cell-cell Junction Membrane Raft Gene Expression
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