NPHS2

Gene Name		nephrosis 2, idiopathic, steroid-resistant (podocin)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Slit Diaphragm Protein Complex Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Protein Binding
	Biological Process	Excretion Actin Cytoskeleton Reorganization Metanephric Glomerular Visceral Epithelial Cell Development
Pathways		Nephrin interactions
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CD2AP KIRREL KIRREL3 NPHS1
Entrez ID		7827
HPRD ID		05303
Ensembl ID		ENSG00000116218
Uniprot IDs		Q9NP85
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Excretion Regulation Of Cytoskeleton Organization Glomerulus Development Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Nephron Development Regulation Of Organelle Organization Positive Regulation Of Protein Complex Assembly Principal Sensory Nucleus Of Trigeminal Nerve Development Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Inter-male Aggressive Behavior Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Transforming Growth Factor Beta Production Kidney Development Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Renal System Development Regulation Of Protein Complex Assembly Urogenital System Development Glomerular Visceral Epithelial Cell Development Positive Regulation Of Organelle Organization Substrate-dependent Cell Migration, Cell Extension Aggressive Behavior Regulation Of Cellular Component Organization Glomerular Basement Membrane Development Glomerular Visceral Epithelial Cell Differentiation Glomerulus Morphogenesis Myoblast Fusion Regulation Of Excretion Syncytium Formation Substrate-dependent Cell Migration Regulation Of Actin Cytoskeleton Reorganization Cell Differentiation Involved In Kidney Development Cell Migration Cell Motility Neural Nucleus Development Myotube Differentiation Cell Projection Organization Cell Adhesion JNK Cascade Locomotion Positive Regulation Of Protein Localization To Nucleus Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade
Tagcloud ?		11t 13c 1678a 181g 279t 35a 38g 48t 718c 86t biotechnology boundaries d93d endonuclease glomerulosclerosis han ivs1 ivs16 ivs18 ivs19 ivs2 ivs25 ivs6 l240f myo1e nephrotic segmental srns t560a