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ZP3 and SPACA3
Number of citations of the paper that reports this interaction (PubMedID
19945174
)
29
Data Source:
BioGRID
(two hybrid)
ZP3
SPACA3
Description
zona pellucida glycoprotein 3
sperm acrosome associated 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Plasma Membrane
Membrane
Extracellular Matrix
Egg Coat
Acrosomal Vesicle
Acrosomal Membrane
Extracellular Region
Membrane
Secretory Granule
Cytoplasmic Vesicle
Sperm Flagellum
Acrosomal Matrix
Molecular Function
Extracellular Matrix Structural Constituent
Protein Binding
Carbohydrate Binding
Acrosin Binding
Structural Constituent Of Egg Coat
Identical Protein Binding
Receptor Ligand Activity
Lysozyme Activity
Protein Binding
Biological Process
Positive Regulation Of Type IV Hypersensitivity
Blastocyst Formation
Humoral Immune Response Mediated By Circulating Immunoglobulin
Positive Regulation Of Leukocyte Migration
Positive Regulation Of Humoral Immune Response
Signal Transduction
Single Fertilization
Binding Of Sperm To Zona Pellucida
Positive Regulation Of Type II Interferon Production
Positive Regulation Of Interleukin-4 Production
Egg Coat Formation
Positive Regulation Of T Cell Proliferation
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Oocyte Development
Positive Regulation Of Inflammatory Response
Positive Regulation Of Acrosome Reaction
Negative Regulation Of Binding Of Sperm To Zona Pellucida
Positive Regulation Of Acrosomal Vesicle Exocytosis
Positive Regulation Of Ovarian Follicle Development
Positive Regulation Of Antral Ovarian Follicle Growth
Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization
Sperm-egg Recognition
Monocyte Activation
Positive Regulation Of Macrophage Activation
Positive Regulation Of Phagocytosis
Pathways
Interaction With Cumulus Cells And The Zona Pellucida
Drugs
Diseases
GWAS
Parkinson disease and lewy body pathology (
25663231
)
Plasma anti-thyroid peroxidase levels (
29678681
)
Red cell distribution width (
32888494
)
Refractive error (
32231278
)
Thyroxine levels (
30843173
)
Interacting Genes
11 interacting genes:
ACR
CLDN11
ENGASE
FURIN
MALL
MICALL1
MRPS16
OR2L13
PCDH17
SPACA3
UBAP2L
1 interacting genes:
ZP3
Entrez ID
7784
124912
HPRD ID
01690
15420
Ensembl ID
ENSG00000188372
ENSG00000141316
Uniprot IDs
P21754
A0A080YUZ7
E9PF91
Q05C28
Q8IXA5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Acrosomal Matrix
Sperm-egg Recognition
Cell-cell Recognition
Cell Recognition
Binding Of Sperm To Zona Pellucida
Acrosome Matrix Dispersal
Negative Regulation Of Nerve Growth Factor Production
Dibasic Protein Processing
Zymogen Inhibition
Mannosyl-glycoprotein Endo-beta-N-acetylglucosaminidase Activity
Cytoplasmic Side Of Endosome Membrane
Amidase Activity
Golgi Apparatus Subcompartment
Regulation Of Nerve Growth Factor Production
Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process
Nerve Growth Factor Production
Negative Regulation Of Neurotrophin Production
Slow Endocytic Recycling
Axon Ensheathment
Negative Regulation Of Receptor Catabolic Process
Presynaptic Active Zone Assembly
Protease Binding
Acrosomal Vesicle
Viral Translation
Viral Life Cycle
Serine-type Peptidase Activity
Plasma Membrane Organization
Cytokine Precursor Processing
Nerve Growth Factor Binding
Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process
Negative Regulation Of Transforming Growth Factor Beta1 Production
Regulation Of Synaptic Vesicle Clustering
Serine-type Endopeptidase Activity
Fucose Binding
Positive Regulation Of Stress Granule Assembly
Lysozyme Activity
Positive Regulation Of Acrosomal Vesicle Exocytosis
Positive Regulation Of Ovarian Follicle Development
Positive Regulation Of Type IV Hypersensitivity
Egg Coat Formation
Acrosin Binding
Positive Regulation Of Antral Ovarian Follicle Growth
Negative Regulation Of Binding Of Sperm To Zona Pellucida
Structural Constituent Of Egg Coat
Egg Coat
Regulation Of Type IV Hypersensitivity
Regulation Of Acrosomal Vesicle Exocytosis
Regulation Of Binding Of Sperm To Zona Pellucida
Humoral Immune Response Mediated By Circulating Immunoglobulin
Regulation Of Ovarian Follicle Development
Positive Regulation Of Hypersensitivity
Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Acrosome Reaction
Positive Regulation Of Inflammatory Response To Antigenic Stimulus
Regulation Of Acrosome Reaction
Oocyte Development
Positive Regulation Of Calcium Ion-dependent Exocytosis
Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Humoral Immune Response
Blastocyst Formation
Positive Regulation Of Acute Inflammatory Response
Positive Regulation Of Interleukin-4 Production
Binding Of Sperm To Zona Pellucida
Regulation Of Interleukin-4 Production
Immunoglobulin Mediated Immune Response
Regulation Of Calcium Ion-dependent Exocytosis
Sperm-egg Recognition
Positive Regulation Of Regulated Secretory Pathway
B Cell Mediated Immunity
Regulation Of Humoral Immune Response
Regulation Of Acute Inflammatory Response
Cell-cell Recognition
Negative Regulation Of Reproductive Process
Positive Regulation Of T Cell Mediated Immunity
Positive Regulation Of Type II Interferon Production
Positive Regulation Of Reproductive Process
Positive Regulation Of Exocytosis
Single Fertilization
Regulation Of T Cell Mediated Immunity
Positive Regulation Of T Cell Proliferation
Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Cell Recognition
Receptor Ligand Activity
Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Regulation Of Type II Interferon Production
Positive Regulation Of Lymphocyte Mediated Immunity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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