SPACA3

Description		sperm acrosome associated 3
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Acrosomal Membrane Extracellular Region Membrane Secretory Granule Cytoplasmic Vesicle Sperm Flagellum Acrosomal Matrix
	Molecular Function	Lysozyme Activity Protein Binding
	Biological Process	Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Sperm-egg Recognition Monocyte Activation Positive Regulation Of Macrophage Activation Positive Regulation Of Phagocytosis
Pathways
Drugs
Diseases
GWAS		Plasma anti-thyroid peroxidase levels ( 29678681) Red cell distribution width ( 32888494) Refractive error ( 32231278) Thyroxine levels ( 30843173)
Interacting Genes		1 interacting genes: ZP3
Entrez ID		124912
HPRD ID		15420
Ensembl ID		ENSG00000141316
Uniprot IDs		A0A080YUZ7 E9PF91 Q05C28 Q8IXA5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Type IV Hypersensitivity Egg Coat Formation Acrosin Binding Positive Regulation Of Antral Ovarian Follicle Growth Negative Regulation Of Binding Of Sperm To Zona Pellucida Structural Constituent Of Egg Coat Egg Coat Regulation Of Type IV Hypersensitivity Regulation Of Acrosomal Vesicle Exocytosis Regulation Of Binding Of Sperm To Zona Pellucida Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Ovarian Follicle Development Positive Regulation Of Hypersensitivity Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Acrosome Reaction Positive Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Acrosome Reaction Oocyte Development Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Humoral Immune Response Blastocyst Formation Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Interleukin-4 Production Binding Of Sperm To Zona Pellucida Regulation Of Interleukin-4 Production Immunoglobulin Mediated Immune Response Regulation Of Calcium Ion-dependent Exocytosis Sperm-egg Recognition Positive Regulation Of Regulated Secretory Pathway B Cell Mediated Immunity Regulation Of Humoral Immune Response Regulation Of Acute Inflammatory Response Cell-cell Recognition Negative Regulation Of Reproductive Process Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Type II Interferon Production Positive Regulation Of Reproductive Process Positive Regulation Of Exocytosis Single Fertilization Regulation Of T Cell Mediated Immunity Positive Regulation Of T Cell Proliferation Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Cell Recognition Receptor Ligand Activity Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Type II Interferon Production Positive Regulation Of Lymphocyte Mediated Immunity
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