ZNF143 and EAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF143	EAF1
Description		zinc finger protein 143	ELL associated factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intercellular Bridge
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Elongation Factor Activity Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Positive Regulation Of SnRNA Transcription By RNA Polymerase II	Transcription Elongation By RNA Polymerase II Regulation Of Transcription Elongation By RNA Polymerase II
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Cutaneous squamous cell carcinoma ( 32041948) Height ( 31562340) Hip circumference ( 28552196)
Interacting Genes		21 interacting genes: EAF1 ENKD1 EXOSC1 FAM90A1 FHL2 IL16 IQUB LIN54 LMO1 LMO3 NUDT22 POGZ SNRPB SPANXN3 SUOX TAB2 TCAF1 TSC22D2 YJU2 ZNF438 ZNF512B	54 interacting genes: AP2M1 APP ARID4B BEND7 CCDC150 CCDC33 CDK9 CEP70 CEP76 DNTTIP1 DPPA4 DRC4 ELL ELL2 FAM228A GADD45GIP1 GCSAML GOLGA6L9 GPRASP3 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM28 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620
Entrez ID		7702	85403
HPRD ID		04578	12209
Ensembl ID		ENSG00000166478	ENSG00000144597
Uniprot IDs		P52747	Q96JC9
PDB IDs			7OKX 7OKY
Enriched GO Terms of Interacting Partners?			Transcription By RNA Polymerase II DNA-templated Transcription Transcription Elongation Factor Complex Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Receptor Internalization TORC1 Complex Assembly Regulation Of RNA Metabolic Process Transcription Elongation By RNA Polymerase II DNA-templated Transcription Elongation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA Binding Regulation Of Receptor-mediated Endocytosis Nucleoplasm Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Receptor Internalization Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Elongation Neuroblast Proliferation SnRNA Transcription By RNA Polymerase II Positive Regulation Of Receptor-mediated Endocytosis Transcription Factor TFIIH Core Complex Regulation Of Macromolecule Metabolic Process Transcription Factor TFIIH Holo Complex Negative Regulation Of Neuroblast Proliferation Nucleus Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process SnRNA Transcription Regulation Of Gene Expression Chromatin Remodeling Positive Regulation Of DNA-templated Transcription, Elongation RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of JNK Cascade Regulation Of Macromolecule Biosynthetic Process Central Nervous System Development Regulation Of Proteolysis Positive Regulation Of Transcription By RNA Polymerase III
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