C21orf2 and ATOX1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		C21orf2	ATOX1
Gene Name		chromosome 21 open reading frame 2	antioxidant 1 copper chaperone
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane	Cytosol
	Molecular Function	Molecular_function	Copper Ion Transmembrane Transporter Activity Copper Ion Binding Metallochaperone Activity Copper Chaperone Activity Copper-dependent Protein Binding
	Biological Process	Cytoskeleton Organization Smoothened Signaling Pathway Regulation Of Cell Shape Cilium Morphogenesis	Response To Reactive Oxygen Species Copper Ion Transport Cellular Copper Ion Homeostasis Response To Oxidative Stress Intracellular Copper Ion Transport Copper Ion Transmembrane Transport
Pathways			Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ATOX1 GMCL1	6 interactors: ATP7A ATP7B C21orf2 FAM118A FKBP4 GGPS1
Entrez ID		755	475
HPRD ID		04427	03779
Ensembl ID		ENSG00000160226	ENSG00000177556
Uniprot IDs		O43822	O00244
PDB IDs			1FE0 1FE4 1FEE 1TL4 1TL5 2K1R 2LQ9 3CJK 3IWL 3IWX
Enriched GO Terms of Interacting Partners?		Intracellular Copper Ion Transport Copper Ion Transmembrane Transport Cellular Copper Ion Homeostasis Copper Ion Homeostasis Copper Ion Transport	Copper Ion Transport Copper Ion Export Copper Ion Transmembrane Transport Copper Ion Import Cellular Copper Ion Homeostasis Copper Ion Homeostasis Response To Copper Ion Lactation Gland Development Body Fluid Secretion Elastin Biosynthetic Process Steroid Hormone Receptor Complex Assembly Plasma Membrane Copper Ion Transport Geranylgeranyl Diphosphate Biosynthetic Process Transition Metal Ion Homeostasis Geranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Metal Ion Transport Mammary Gland Development Elastin Metabolic Process Detoxification Of Copper Ion Response To Iron(III) Ion Sequestering Of Calcium Ion Epinephrine Metabolic Process Intracellular Copper Ion Transport Farnesyl Diphosphate Metabolic Process Cation Transport Norepinephrine Biosynthetic Process Negative Regulation Of Metalloenzyme Activity Elastic Fiber Assembly Positive Regulation Of Metalloenzyme Activity Response To Metal Ion Regulation Of Oxidative Phosphorylation Sequestering Of Metal Ion Tyrosine Metabolic Process Pyramidal Neuron Development Pyramidal Neuron Differentiation Norepinephrine Metabolic Process Cellular Metal Ion Homeostasis Negative Regulation Of Microtubule Polymerization Cellular Zinc Ion Homeostasis Cerebellar Purkinje Cell Differentiation Serotonin Metabolic Process Cellular Cation Homeostasis Extracellular Matrix Assembly Cellular Ion Homeostasis Zinc Ion Homeostasis Cerebellar Purkinje Cell Layer Morphogenesis Ion Transport Metal Ion Homeostasis
Tagcloud ?			accumulated affects allowing chains chaperones chelated cisplatin compartments copper cu decays elucidation embryonic emission exist fibroblast hct nuclei nucleus optimizing owing positron radionuclide radiopharmaceuticals tomography traffic transport transporting upregulating
Tagcloud (Difference) ?			accumulated affects allowing chains chaperones chelated cisplatin compartments copper cu decays elucidation embryonic emission exist fibroblast hct nuclei nucleus optimizing owing positron radionuclide radiopharmaceuticals tomography traffic transport transporting upregulating
Tagcloud (Intersection) ?