ATOX1

Gene Name		antioxidant 1 copper chaperone
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Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Copper Ion Transmembrane Transporter Activity Copper Ion Binding Metallochaperone Activity Copper Chaperone Activity Copper-dependent Protein Binding
	Biological Process	Response To Reactive Oxygen Species Copper Ion Transport Cellular Copper Ion Homeostasis Response To Oxidative Stress Intracellular Copper Ion Transport Copper Ion Transmembrane Transport
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: ATP7A ATP7B C21orf2 FAM118A FKBP4 GGPS1
Entrez ID		475
HPRD ID		03779
Ensembl ID		ENSG00000177556
Uniprot IDs		O00244
PDB IDs		1FE0 1FE4 1FEE 1TL4 1TL5 2K1R 2LQ9 3CJK 3IWL 3IWX
Enriched GO Terms of Interacting Partners?		Copper Ion Transport Copper Ion Export Copper Ion Transmembrane Transport Copper Ion Import Cellular Copper Ion Homeostasis Copper Ion Homeostasis Response To Copper Ion Lactation Gland Development Body Fluid Secretion Elastin Biosynthetic Process Steroid Hormone Receptor Complex Assembly Plasma Membrane Copper Ion Transport Geranylgeranyl Diphosphate Biosynthetic Process Transition Metal Ion Homeostasis Geranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Metal Ion Transport Mammary Gland Development Elastin Metabolic Process Detoxification Of Copper Ion Response To Iron(III) Ion Sequestering Of Calcium Ion Epinephrine Metabolic Process Intracellular Copper Ion Transport Farnesyl Diphosphate Metabolic Process Cation Transport Norepinephrine Biosynthetic Process Negative Regulation Of Metalloenzyme Activity Elastic Fiber Assembly Positive Regulation Of Metalloenzyme Activity Response To Metal Ion Regulation Of Oxidative Phosphorylation Sequestering Of Metal Ion Tyrosine Metabolic Process Pyramidal Neuron Development Pyramidal Neuron Differentiation Norepinephrine Metabolic Process Cellular Metal Ion Homeostasis Negative Regulation Of Microtubule Polymerization Cellular Zinc Ion Homeostasis Cerebellar Purkinje Cell Differentiation Serotonin Metabolic Process Cellular Cation Homeostasis Extracellular Matrix Assembly Cellular Ion Homeostasis Zinc Ion Homeostasis Cerebellar Purkinje Cell Layer Morphogenesis Ion Transport Metal Ion Homeostasis
Tagcloud ?		accumulated affects allowing chains chaperones chelated cisplatin compartments copper cu decays elucidation embryonic emission exist fibroblast hct nuclei nucleus optimizing owing positron radionuclide radiopharmaceuticals tomography traffic transport transporting upregulating